甘肃中医药大学机构知识库

成果/Result

1Design of novel antimicrobial peptide dimer analogues with enhanced antimicrobial activity in vitro and in vivo by intermolecular triazole bridge strategy被引量：43收藏 分享

作者：Liu, Beijun Huang, Haifeng Yang, Zhibin Liu, Beiyin Gou, Sanhu

机构：Lanzhou Univ;Lanzhou Univ;Shaanxi Prov Peoples Hosp;Dali Univ;Gansu Univ Chinese Med

来源：PEPTIDES  2017年88卷

JCR：二分区

影响因子：2.851

关键词：Click chemistry   Dimer analogues   Antimicrobial activity   alpha Helical structure   Drug resistance  

2Intramolecular cyclization of the antimicrobial peptide Polybia-MPI with triazole stapling: influence on stability and bioactivity被引量：28收藏 分享

作者：Liu, Beijun Zhang, Wei Gou, Sanhu Huang, Haifeng Yao, Jia

机构：Lanzhou Univ;Lanzhou Univ;Shaanxi Prov Peoples Hosp;Lanzhou Univ;Dali Univ

来源：JOURNAL OF PEPTIDE SCIENCE  2017年23卷11期

JCR：三分区

影响因子：1.969

关键词：antimicrobial peptides   intramolecular cyclization   click chemistry   stability   antimicrobial activity   secondary structure   mechanism of action