文献类型：期刊文献

英文题名：Effect of Chinese Medicine Spatholobus Preparation on Cerebrospinal Fluid Immunoglobulin in Patients with Multiple Sclerosis

作者：Zhang, Rong[1];Xue, Na[2]

第一作者：Zhang, Rong

通信作者：Zhang, R[1]

机构：[1]Lanzhou Petrochem Hosp, Dept Neurol, Lanzhou 730050, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Preclin Med Coll, Lanzhou 730101, Gansu, Peoples R China

第一机构：Lanzhou Petrochem Hosp, Dept Neurol, Lanzhou 730050, Gansu, Peoples R China

通信机构：[1]Lanzhou Petrochem Hosp, Dept Neurol, Lanzhou 730050, Gansu, Peoples R China.

年份：2019

卷号：59

期号：3

起止页码：50

外文期刊名：BOLETIN DE MALARIOLOGIA Y SALUD AMBIENTAL

收录：;Scopus(收录号：2-s2.0-85073220065);WOS:【SCI-EXPANDED(收录号:WOS:000478082900009)】；

语种：英文

外文关键词：Multiple sclerosis; traditional Chinese medicine spatholobus preparation; immunoglobulin; immune function

摘要：The diagnosis of multiple sclerosis is very difficult. The early imaging and routine examination of the lesion cannot be diagnosed, and the increase of immunoglobulin IgG in the cerebrospinal fluid of the patient occurs. The cerebrospinal fluid protein electrophoresis IgG forms a typical oligoclonal zone, which is important for early diagnosis. Basis. This paper analyzes the effect of Chinese medicine spatholobus preparation on cerebrospinal fluid immunoglobulin in patients with multiple sclerosis. We observed the clinical comprehensive efficacy and clinical symptoms, neurological signs and neurological dysfunction scores before and after treatment and evoked potentials, magnetic resonance imaging, cerebrospinal fluid immunoglobulin G and recurrence and other indicators. The results showed that in the treatment group, the effective rate was 85%, and the difference between the two groups was very significant (p<0.01). After treatment, the clinical symptoms, neurological signs, EDSS scores and total scores of the two groups were decreased. Compared with before treatment, the difference was significant or very significant (p<0.01). Conclusion: Traditional Chinese medicine spatholobus preparation for the treatment of multiple sclerosis can not only effectively improve clinical symptoms and signs, restore nerve function, but also have different degrees of improvement and recovery of evoked potentials, cerebrospinal fluid and oligoclonal bands and examinations, and can also reduce the number of recurrences reduces the recurrence rate.