文献类型：期刊文献

英文题名：Efficiently electron beam radiation-induced degradation and extraction of Angelica sinensis polysaccharides and its excellent biofunctional properties

作者：Hu, Yunxia[1,2];Liu, Xiao[1,3];Wang, Haijun[4];Xin, Zhijun[1,3];Chen, Fanglei[5];Hu, Fangli[1,6];Liu, Bingkun[4];Lu, Xihong[1,3];Du, Mengmeng[1,6];Ren, Xinshuo[1,6];Wang, Zhuanzi[1,3];Li, Xuehu[1,3];Yang, Aimei[2];Zhou, Libin[1,3,7]

第一作者：Hu, Yunxia

通信作者：Li, XH[1];Zhou, LB[1];Yang, AM[2]

机构：[1]Chinese Acad Sci, Inst Modern Phys, Biophys Grp, Lanzhou 730000, Peoples R China;[2]Lanzhou Univ Technol, Sch Life Sci & Engn, Lanzhou 730050, Peoples R China;[3]Univ Chinese Acad Sci, Beijing 101408, Peoples R China;[4]Gansu Puankang Pharmaceut Co Ltd, Lanzhou 730207, Peoples R China;[5]State Nucl Secur Technol Ctr, Beijing 102401, Peoples R China;[6]Gansu Univ Chinese Med, Coll Pharm, Lanzhou, Peoples R China;[7]Chinese Acad Sci, Inst Modern Phys, State Key Lab Heavy Ion Sci & Technol, Lanzhou 730000, Peoples R China

第一机构：Chinese Acad Sci, Inst Modern Phys, Biophys Grp, Lanzhou 730000, Peoples R China

通信机构：[1]corresponding author), Chinese Acad Sci, Inst Modern Phys, Biophys Grp, Lanzhou 730000, Peoples R China;[2]corresponding author), Lanzhou Univ Technol, Sch Life Sci & Engn, Lanzhou 730050, Peoples R China.

年份：2026

卷号：521

外文期刊名：FOOD CHEMISTRY

收录：;EI(收录号：20262320855637);Scopus(收录号：2-s2.0-105041114869);WOS:【SCI-EXPANDED(收录号:WOS:001791071800001)】；

基金：The authors gratefully acknowledge the Nuclear Technology R & D Program (HJSYF2024(31)) , Technology Development Project of Gansu Puankang Pharmaceutical Co., Ltd. (IMPSK2024073) , Inner Mongolia National Science Foundation (2024ZD23) .

语种：英文

外文关键词：Angelica sinensis polysaccharides; Biofunctional properties; Degradation; Electron beam irradiation; Extraction

摘要：The full exploitation of botanical polysaccharides is often hampered by inefficient extraction and limited structural controllability. This study investigated electron beam irradiation (EBI, 0-80 kGy) as a green pretreatment to enhance extraction yield and modify biofunctional properties of Angelica sinensis polysaccharides. EBI enhanced extraction yield by 62.13%, while reducing molecular weight by 46.61%, enhancing solubility and oil holding capacity. Notably, EBI triggered a dose-dependent reconstruction of monosaccharide composition, including a 42.01% increase in arabinose, without altering the fundamental functional groups or triple-helix conformation. This structural modulation led to divergent functional enhancements, medium-dose irradiation (40 kGy) markedly improved immunomodulatory activity and foaming capacity/stability, whereas high-dose irradiation (80 kGy) greatly enhanced antioxidant activity and antitumor efficacy against K562 cells. The strong correlations established between structural parameters and bioactivities underscore a controllable structure-activity relationship. These findings provide a novel strategy for the value-added development of functional food ingredients.