文献类型：期刊文献

中文题名：慢性糜烂性胃炎舌象与胃黏膜病理形态学相关性研究

英文题名：The Study On The Relationship Between The Chronic Erosive Gastritis And Gastric Mucosa Pathomorphology

作者：张志明[1];梁建庆[1];陈嘉屿[2];王鑫[3];彭义平[4]

第一作者：张志明

机构：[1]甘肃中医学院附属医院急诊科;[2]兰州军区兰州总医院消化科;[3]甘肃中医学院;[4]西北师范大学网络教育学院,兰州730000

第一机构：甘肃中医药大学第二附属医院

年份：2013

卷号：27

期号：3

起止页码：7

中文期刊名：实用中医内科杂志

外文期刊名：Journal of Practical Traditional Chinese Internal Medicine

基金：甘肃省科技厅课题(No:1010RJZA176)

语种：中文

中文关键词：慢性糜烂性胃炎;舌象;胃黏膜病理形态学;肠上皮化生;胃黏膜炎细胞浸润;相关性研究

外文关键词：Chronic erosive gastritis; Tongue; Gastric mucosa pathological morphology; Intestinal meta-plasia; Gastric mucosa inflammatory cell infiltration; Correlation study

摘要：[目的]研究慢性糜烂性胃炎舌象与胃黏膜病理形态学相关性。[方法]使用系统分析方法,将90例慢性糜烂性胃炎门诊患者根据舌象辨证分为5组:舌红苔黄-实热证组(48例),舌淡苔黄-寒热夹杂证组(16例),舌淡苔白滑-虚寒证组(10例),舌质紫暗-血瘀证组(8例),舌红少苔-阴虚证组(8例)。采集胃黏膜活检标本,根据胃黏膜萎缩和肠化程度分为无(0),轻度(+)、中度(++)、重度(+++)。[结果]舌质紫暗-血瘀组和舌红少苔-阴虚组,胃黏膜萎缩程度较为严重,与其它各组存在显著性差异(P<0.01)。除17例无肠化生外,其余73例均发生了不同程度的肠上皮化生,肠化率高达81.11%(73/90);舌质紫暗-血瘀组和舌红少苔-阴虚组肠化生程度均在(++)以上,与其他各组有显著性差异(P<0.01)。舌红苔黄(包括薄黄、黄腻)-实热证组和舌红少苔-阴虚组中,胃黏膜急性炎细胞浸润程度较为明显,与其他各组有显著性差异(P<0.01)。舌质紫暗-血瘀组和舌红少苔-阴虚组,胃黏膜淋巴细胞浸润不明显,与其他各组存在显著差异(P<0.01)。[结论]慢性糜烂性胃炎中医证型舌象与胃黏膜病理形态学改变可建立客观化、定量化的相关性指标。
[Objective]Chronic erosive gastritis and tongue and gastric mucosa pathological morphological relations,for clinical diagnosis and treatment with syndrome differentiation on the basis of.[Methods]Observation on 90cases of chronic erosive gastritis in patients with tongue,according to the different tongue were divided into 5 groups： a syndrome of excessive heat,cold and heat syndrome of intermingled group,group of group,blood stasis,deficiency of Yin group group.Observed in the gastric mucosa pathological changes,to find the correlation between the two.[Result] On 90 cases of chronic erosive gastritis patients of the tongue and gastric mucosa pathological statistical analysis of data shows that： the red tongue yellow consisting mainly of damp-heat syndrome group and red tongue without fur consisting mainly of yin deficiency syndrome of group acute gastric mucosal inflammatory cell infiltration is more obvious,and other groups were significantly different（P〈0.01）.Tongue dark purple for the characteristics of the blood stasis syndrome group,red tongue without fur Yin deficiency syndrome group of mucosal atrophy and intestinal metaplasia of the more severely,and lymphocytic infiltration was not obvious,and the other groups had significant difference（P〈0.01）.[Conclusion]The results of this study can provide chronic erosive gastritis syndrome differentiation to provide objective,quantitative index.