文献类型：期刊文献

中文题名：Effects of bone marrow cells transplantation for acute myocardial infarction on cardiac function,infarct size,and clinical events:a metaanalysis

作者：Shuxia Wang[1,2];Jihong Hu[1,3];Genxi Dong[4];Mingyan Ma[1];Xuelian Chen[1];Fengfeng Ding[1]

第一作者：Shuxia Wang

机构：[1]Public Health School,Gansu University of Chinese Medicine,Lanzhou,Gansu 730000,China;[2]Affiliated Hospital of Gansu University of Chinese Medicine,Lanzhou,Gansu 730000,China;[3]Center of Research and Experiment,Gansu University of Chinese Medicine,Lanzhou,Gansu 730000,China;[4]School&Hospital of Stomatology Lanzhou University,Lanzhou,Gansu 730000,China

第一机构：甘肃中医药大学

年份：2023

卷号：136

期号：20

起止页码：2518

中文期刊名：Chinese Medical Journal

外文期刊名：中华医学杂志（英文版）

收录：CSTPCD;;Scopus;CSCD:【CSCD2023_2024】；PubMed;

基金：supported by grants from the National Natural Science Foundation of China(No.81960614);International scientific and technological cooperation project(No.20YF3WA020).

语种：英文

中文关键词：cardiac;clinical;myocardial;

摘要：To the Editor:Acute myocardial infarction(AMI)poses a substantial threat to human health.^([1])At present,AMI is mainly treated by reperfusion,drugs,and surgery,^([2])which only temporarily delay cell death and deterioration.Sian Harding at el^([3])suggested that myocardial transfer of specific bone marrow cells(BMCs)and progenitor cell populations may enhance recovery of systolic and diastolic function after AMI.Although a few previous meta-analysis studies of BMCs transplantation for AMI have been published,the quality of these studies was varied due to marked heterogeneity^([4,5])or because they focused on a single outcome(e.g.,cardiac function)[5]and very few evaluated the clinical evens.^([6])In addition,the effects of BMCs transplantation over different lengths of follow-up periods were unclear.In an attempt to reach more reliable conclusions,we performed an updated meta-analysis of randomized controlled trials(RCTs)and conducted subgroup analyses according to follow-up periods.