文献类型：期刊文献

英文题名：Biomechanical effects of different vertebral heights after augmentation of osteoporotic vertebral compression fracture: a three-dimensional finite element analysis

作者：Zhao, Wen-Tao[1,3];Qin, Da-Ping[1,2];Zhang, Xiao-Gang[1,2];Wang, Zhi-Peng[1,2];Tong, Zun[1,2]

第一作者：Zhao, Wen-Tao

通信作者：Zhang, XG[1];Zhang, XG[2]

机构：[1]Gansu Univ Chinese Med, 35 Dingxi East Rd, Lanzhou 730000, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Affiliated Hosp, 735 Jiayuguan West Rd, Lanzhou 730000, Gansu, Peoples R China;[3]Yunnan Univ Tradit Chinese Med, 1076 Yuhua Rd, Kunming 650500, Yunnan, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, 35 Dingxi East Rd, Lanzhou 730000, Gansu, Peoples R China;[2]corresponding author), Gansu Univ Chinese Med, Affiliated Hosp, 735 Jiayuguan West Rd, Lanzhou 730000, Gansu, Peoples R China.|[10735b845793de6ae2b30]甘肃中医药大学第二附属医院;[10735]甘肃中医药大学;

年份：2018

卷号：13

期号：1

外文期刊名：JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH

收录：;Scopus(收录号：2-s2.0-85041861436);WOS:【SCI-EXPANDED(收录号:WOS:000425104100002)】；

基金：This work was supported by the National Natural Science Foundation of China (81560780).

语种：英文

外文关键词：Vertebral augmentation; Von Mises stress; Osteoporotic vertebral compression fracture

摘要：Background: Clinical results have shown that different vertebral heights have been restored post-augmentation of osteoporotic vertebral compression fractures (OVCFs) and the treatment results are consistent. However, no significant results regarding biomechanical effects post-augmentation have been found with different types of vertebral deformity or vertebral heights by biomechanical analysis. Therefore, the present study aimed to investigate the biomechanical effects between different vertebral heights of OVCFs before and after augmentation using three-dimensional finite element analysis. Methods: Four patients with OVCFs of T12 underwent computed tomography (CT) of the T11-L1 levels. The CT images were reconstructed as simulated three-dimensional finite-element models of the T11-L1 levels (before and after the T12 vertebra was augmented with cement). Four different kinds of vertebral height models included Genant semi-quantitative grades 0, 1, 2, and 3, which simulated unilateral augmentation. These models were assumed to represent vertical compression and flexion, left flexion, and right flexion loads, and the von Mises stresses of the T12 vertebral body were assessed under different vertebral heights before and after bone cement augmentation. Results: Data showed that the von Mises stresses significantly increased under four loads of OVCFs of the T12 vertebral body before the operation from grade 0 to grade 3 vertebral heights. The maximum stress of grade 3 vertebral height pre-augmentation was produced at approximately 200%, and at more than 200% for grade 0. The von Mises stresses were significantly different between different vertebral heights preoperatively. The von Mises stresses of the T12 vertebral body significantly decreased in four different loads and at different vertebral body heights (grades 0-3) after augmentation. There was no significant difference between the von Mises stresses of grade 0, 1, and 3 vertebral heights postoperatively. The von Mises stress significantly decreased between pre-augmentation and post-augmentation in T12 OVCF models of grade 0-3 vertebral heights. Conclusion: Vertebral augmentation can sufficiently reduce von Mises stresses at different heights of OVCFs of the vertebral body, although this technique does not completely restore vertebral height to the anatomical criteria.