文献类型：期刊文献

中文题名：当归藁本内酯抗老年痴呆作用研究进展

英文题名：Advances in Effect of Ligustilide of Radix Angelicae Sinensis on Prevention and Treatment of Senile Dementia

作者：荔淑楠[1];马骏[1];臧凯宏[1];王引权[1];张秋菊[2];樊秦[3];夏琦[3]

第一作者：荔淑楠

机构：[1]甘肃中医学院药学院,甘肃兰州730000;[2]甘肃中医学院基础医学院,甘肃兰州730000;[3]甘肃中医学院科研实验中心,甘肃兰州730000

第一机构：甘肃中医药大学药学院（西北中藏药协同创新中心办公室）

年份：2016

卷号：18

期号：5

起止页码：674

中文期刊名：中国现代中药

外文期刊名：Modern Chinese Medicine

收录：CSTPCD

基金：国家自然科学基金项目(81060327;81260616)

语种：中文

中文关键词：当归;藁本内酯;老年痴呆;药理作用

外文关键词：Angelica sinensis ; ligustilide; senile dementia ; pharmacological effects

摘要：当归藁本内酯是当归挥发油的主要活性成分,其在当归中的含量较高。随着当归藁本内酯提取、贮存技术的发展,藁本内酯的药理作用研究越来越受到人们的关注,前人对其降压、镇痛、平喘、消炎、解热、抗菌、镇静、催眠等的药理作用作过较多综述,本文就近年来当归藁本内酯对老年痴呆药理作用的研究展开综述,为其治疗老年痴呆提供参考。
Ligustilide is the main active ingredient in essential oil of Radix Angelicae Sinensis, and the content is quite higher. Along with the development of ligustilide extraction and storage technology, more attentions have been paid to pharmacological effects of ligustilide. Previous literature reviews have been made on pharmacological effects of ligustilide on lowering blood pressure, analgesia, relieving asthma, anti-inflammation, antipyresis, relieving pressure, antipyretic, antibiosis, sedation and hypnosis and so on. This review summarizes the advances in effect of ligustilide of Radix Angelicae Sinensis on prevention and treatment of senile dementia in recent years, which can provide the references for prevention and treatment of senile dementia.