文献类型：期刊文献

英文题名：Residential greenspace and blood lipids in an essential hypertension population: Mediation through PM2.5 and chemical constituents

作者：Lei, Ruoyi[1]; Zhang, Ling[1]; Liu, Xin[2]; Liu, Ce[1]; Xiao, Ya[1]; Xue, Baode[1]; Wang, Zengwu[3]; Hu, Jihong[4]; Ren, Zhoupeng[5]; Luo, Bin[1,6,7]

第一作者：Lei, Ruoyi

机构：[1] Institute of Occupational Health and Environmental Health, School of Public Health, Lanzhou University, Gansu, Lanzhou, 730000, China; [2] School of Spatial Planning and Design, Hangzhou City University, Zhejiang, Hangzhou, 310015, China; [3] Division of Prevention and Community Health, National Center for Cardiovascular Disease, Fuwai Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, 100037, China; [4] School of Public Health, Gansu University of Chinese Medicine, Gansu, Lanzhou, 730000, China; [5] State Key Laboratory of Resources and Environmental Information System [LREIS], Institute of Geographic Science and Natural Resource Research, Chinese Academy of Sciences, Beijing, 100101, China; [6] Shanghai Key Laboratory of Meteorology and Health, Shanghai Meteorological Bureau, Shanghai, 200030, China; [7] Shanghai Typhoon Institute, China Meteorological Administration, Shanghai, 200030, China

第一机构：Institute of Occupational Health and Environmental Health, School of Public Health, Lanzhou University, Gansu, Lanzhou, 730000, China

通信机构：[5]State Key Laboratory of Resources and Environmental Information System (LREIS), Institute of Geographic Science and Natural Resource Research, Chinese Academy of Sciences, Beijing, 100101, China

年份：2024

卷号：240

外文期刊名：Environmental Research

收录：EI(收录号：20234414984877);Scopus(收录号：2-s2.0-85175034454)

语种：英文

外文关键词：Blood - Housing - Particles (particulate matter)

摘要：Fine particulate matter (PM2.5) adversely affects blood lipids, while residential greenspace exposure may improve blood lipids levels. However, the association between exposure to residential greenspace and blood lipids has not been adequately studied, especially in vulnerable populations (e.g. people with essential hypertension). This study aimed to assess the association between residential greenspace exposure and blood lipids, and to clarify whether PM2.5 and chemical constituents was mediator of it. We used a period (May 2010 to December 2011) from the Chinese national hypertension project. The residential greenspace was estimated using satellite-derived normalized difference vegetation index (NDVI). The generalized additive mixed model (GAMM) was used to assess the association between exposure to residential greenspace and blood lipids, and the mediation model was used to examine whether there was a mediating effect of PM2.5 and chemical constituents on that association. The exposure to residential greenspace was negatively associated with the decreased risk of dyslipidemia, especially short-term exposure. For example, the odd ratioshort-term for dyslipidemia was 0.915 (95% CI：0.880 to 0.950). This association was strengthened by physical activity and participants living in the North. PM2.5 and chemical constituents were important mediators in this association, with the proportion of mediators ranging from ?5.02% to 26.33%. The association between exposure to residential greenspace and dyslipidemia in this essential hypertensive population, especially participants living in the North and doing daily physical activity, was mediated by PM2.5 and chemical constituents. ? 2023 Elsevier Inc.