文献类型：期刊文献

中文题名：均匀设计优化超临界CO_2流体萃取大黄蒽醌的研究

英文题名：Study on the Uniformity Design Optimization CO_2 Fluid Extract of Pieplant Anthraquinone

作者：陈卫林[1];郭玫[1];赵磊[1];余晓晖[1];杨荣[1];张梦云[1];张玉兰[1];王颖[1]

第一作者：陈卫林

机构：[1]甘肃中医学院

第一机构：甘肃中医药大学

年份：2007

卷号：13

期号：2

起止页码：72

中文期刊名：中医药导报

外文期刊名：Guiding Journal of TCM

收录：CSTPCD

语种：中文

中文关键词：超临界CO2流体;SFE;掌叶大黄;均匀设计;大黄蒽醌

外文关键词：SFE - CO2 ; SFE; Rheum palmatum L; uniformity design; Anthraquinone of pieplant

摘要：目的:通过均匀设计试验确定超临界二氧化碳流体萃取(SFE-CO2)掌叶大黄中蒽醌类成分的最佳提取工艺条件。方法:以药材粒度、萃取压力、萃取温度、萃取时间和夹带剂用量为考察因素,进行SFE-CO2萃取;用高效液相色谱法测定不同条件下芦荟大黄素、大黄酸、大黄素、大黄酚、大黄素甲醚的含量。结果:优选出总蒽醌的最佳萃取工艺条件是萃取压力为38 MPa,萃取温度为70℃,萃取时间为60 m in;夹带剂用量为300 m l。结论:最佳提取工艺可有效萃取掌叶大黄中蒽醌类成分;本含量测定方法可靠、简单易行。
Objective： To use the uniformity design test for deciding the best extract technology conditions of pieplant anthraquinone. Method： The inspective factors included granularity of medical material, extractive pressure, extractive temperature and time, dosage of entrainer. SFE - CO2 was used for extracting. HPLC method used to determine the contents of aloe - emodin, chrysophanic acid, archen, chrysophanol, physcione in different conditions. Result： The best extract technology conditions involved that the extrac- tive pressure was 38 MPa, the extractive temperature and time were 70 ℃ and 60 minutes respectively with the dosage of entrainer 300 ml. Conclusion： The best extracting technology can extract the anthraquinone elements in Rheum palmatum L. The method is reliable and simple.