文献类型：期刊文献

中文题名：Integration of metabolomics and transcriptomics reveals major metabolic pathways and potential biomarkers involved in aging mice with type 2 diabetes mellitus

作者：Jie Meng[1];Jiajia Liu[1];Dongmei Chen[1];Dandan Li[1];Jing Wang[1,2]

第一作者：Jie Meng

机构：[1]School of Clinical Medicine,Gansu University of Chinese Medicine,Lanzhou,Gansu 730000,China;[2]Key Laboratory of Traditional Chinese Herbs and Prescription Innovation and Transformation of Gansu Province,Gansu University of Chinese Medicine,Lanzhou,Gansu 730000,China

第一机构：甘肃中医药大学

年份：2022

卷号：135

期号：2

起止页码：247

中文期刊名：中华医学杂志:英文版

外文期刊名：Chinese Medical Journal

收录：CSTPCD;;Scopus;CSCD:【CSCD2021_2022】；PubMed;

基金：This work was supported by grants from the National Natural Science Foundation of China(Nos.81760835,82060829);Postgraduate Innovation Fund of Gansu University of Chinese Medicine(No.CX2020-45);Natural Science Foundation of Gansu Province(No.1606RJZA192).

语种：英文

中文关键词：T2DM;mellitus;diabetes;

摘要：To the Editor:Aging can cause changes in human metabolic capacity[1]and metabolic syndrome is one of the important causes of type 2 diabetes mellitus(T2DM).In recent years,T2DM has become one of the top ten killers of humans.[2]T2DM has been reported in≥25%of the population aged over 65 years.[3]The liver is the most important metabolic center and its metabolic disorders are associated with T2DM.