文献类型：期刊文献

中文题名：我国社区门诊就诊高血压患者的用药现状

英文题名：Current status on the use of antihypertensive drugs in community outpatient with hypertension in China

作者：周好奇[1];王馨[1];杨瑛[1];张林峰[1];陈祚[1];李苏宁[1];王伟[1];郑聪毅[1];亢玉婷[1];陈露[1];蔡佳音[1];曹雪[1];陈雪莲[2];马明艳[2];田野[1];邵澜[1];王增武[1]

第一作者：周好奇

机构：[1]中国医学科学院北京协和医学院阜外医院,国家心血管病中心,社区防治部,北京100037;[2]甘肃中医药大学公共卫生学院

第一机构：中国医学科学院北京协和医学院阜外医院,国家心血管病中心,社区防治部,北京100037

年份：2022

卷号：30

期号：7

起止页码：670

中文期刊名：中华高血压杂志

外文期刊名：Chinese Journal of Hypertension

收录：CSTPCD;;北大核心:【北大核心2020】；CSCD:【CSCD2021_2022】；

基金：中国医学科学院医学与健康科技创新工程项目(2017-I2M-1-004)。

语种：中文

中文关键词：高血压;门诊;降压药;联合用药

外文关键词：hypertension;outpatient clinic;antihypertensive drug;combination therapy

摘要：目的 了解我国基层社区门诊就诊高血压患者用药现状及用药与指南推荐不一致的情况。方法 基于“中国医学科学院医学与健康科技创新工程”项目,从2018年8月至2020年12月,在全国范围内选取25个区县,纳入高血压、冠状动脉粥样硬化性心脏病高危对象进行研究。收集调查对象的基本信息及高血压患者服用降压药的名称、剂量和频率。分析高血压患者中不同类型降压药的使用频次、联合模式及用药与指南推荐不一致的情况。结果本次研究共纳入高血压患者4 518例,年龄为(61.7±9.4)岁,男性占45.2%。2 930例高血压患者正在接受药物治疗,其中68.3%为单药治疗。接受单药治疗的患者中,钙通道阻滞剂(CCB)使用比例最高,占59.2%;联合用药以血管紧张素受体阻滞药联合CCB最常见,占24.7%。有5.3%的高血压患者药物选择与指南推荐不一致。结论我国社区门诊就诊高血压患者中用药以单药治疗为主,降压药的使用存在与指南推荐不一致的情况。
Objective To understand the current status of the use of antihypertensive drugs as well as the inconsistency between medication and recommendation of China guideline on hypertension in community hypertensive patients. Methods Based on “CAMS Innovation Fund for Medical Science” program, subjects with hypertension or at high risk of coronary heart disease from 25 districts and counties nationwide were included from August 2018 to December 2020. Basic information of subjects and data(names, doses and frequency of antihypertensive drugs) were collected. Information on the frequency, combination patterns of different antihypertensive drugs, and the inconsistency between antihypertensive medication and guideline recommendation were analyzed. Results A total of 4 518 subjects with hypertension were included in the study [mean age(61.7±9.4) years, 45.2% were male]. Among 2 930 hypertensive patients taking medication, 68.3% were on monotherapy. Calcium channel blockers(CCB, 59.2%) was the most frequently used antihypertensive drug in patients with single drug therapy, while angiotensin receptor blockers combined with CCB were the most common(24.7%) in combination therapy. Medications were inconsistent with the guideline recommendation in 5.3% of patients. Conclusion The hypertensive patients are mainly treated with single durg in China primary community outpatient clinics, and the inconsistency between antihypertensive drugs use and guideline recommendation still exist.