文献类型：期刊文献

英文题名：Renal Yolk Sac Tumor Clinically Misdiagnosed as Nephroblastoma: A Case Report

作者：Zhu, Meng[1,2];Xia, Chengmao[1,2];Yang, Jie[1];Liu, Zhe[1];Zhao, Xiaowen[1];Li, Yaling[1];Liu, Bin[2];Yang, Yanli[2];She, Yali[1,3]

第一作者：Zhu, Meng

通信作者：She, YL[1]

机构：[1]Gansu Univ Chinese Med, Clin Med Coll 1, Dept Pathol, Lanzhou, Gansu, Peoples R China;[2]940 Hosp, Dept Pathol, Chinese Peoples Liberat Army Joint Logist Support, Lanzhou, Gansu, Peoples R China;[3]35 dingxi east Rd, Lanzhou, Gansu, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), 35 dingxi east Rd, Lanzhou, Gansu, Peoples R China.

年份：2023

卷号：42

期号：3

起止页码：522

外文期刊名：FETAL AND PEDIATRIC PATHOLOGY

收录：;Scopus(收录号：2-s2.0-85146320722);WOS:【SCI-EXPANDED(收录号:WOS:000913090800001)】；

语种：英文

外文关键词：yolk sac tumor; endodermal sinus tumor; kidney tumor; germ cell tumor; renal blast; misdiagnosis

摘要：Background: Yolk sac tumor is a germ cell tumor (GCT) that occurs in infants and adolescents and affects various sites. There is a trend to treat pediatric renal tumors before a tissue diagnosis. We report a renal yolk sac tumor clinically misdiagnosed as Wilms tumor, based on ultrasound (US) and MRI.Case Report: This 21-month-old male infant was discovered to have a space occupying lesion in the right kidney. Because the tumor was large, initial radiotherapy preceded surgical resection. Histologically, the tumor was a yolk sac tumor.Conclusion: Imaging examination of renal yolk sac tumor can easily be misdiagnosed as Wilms tumor. SIOP treatment plan for Wilms tumor requires preoperative chemotherapy, which is different from the treatment regimen for yolk sac tumor. Preoperative alpha-fetoprotein could have been helpful in avoiding this clinical misdiagnosis.