文献类型：期刊文献

英文题名：Case Report: A case of incidentally discovered isolated gastric plasmacytoma

作者：Zhang, Ya-nan[1,2,3];Li, Qing-xin[1,2];Ma, Lin-chong[1,2];Jin, Yong-tai[1,2,3];Li, Wen-qi[1,2,3];Du, Jin-chen[1,2]

第一作者：张亚男;Zhang, Ya-nan

通信作者：Du, JC[1];Du, JC[2]

机构：[1]940th Hosp Joint Logist Support Force, Dept High Altitude Med, Chinese Peoples Liberat Army, Lanzhou, Gansu, Peoples R China;[2]940th Hosp Joint Logist Support Force, Dept Thorac Surg, Chinese Peoples Liberat Army, Lanzhou, Gansu, Peoples R China;[3]Gansu Univ Tradit Chinese Med, Clin Coll 1, Lanzhou, Gansu, Peoples R China

第一机构：940th Hosp Joint Logist Support Force, Dept High Altitude Med, Chinese Peoples Liberat Army, Lanzhou, Gansu, Peoples R China

通信机构：[1]corresponding author), 940th Hosp Joint Logist Support Force, Dept High Altitude Med, Chinese Peoples Liberat Army, Lanzhou, Gansu, Peoples R China;[2]corresponding author), 940th Hosp Joint Logist Support Force, Dept Thorac Surg, Chinese Peoples Liberat Army, Lanzhou, Gansu, Peoples R China.

年份：2026

卷号：16

外文期刊名：FRONTIERS IN ONCOLOGY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001825095900001)】；

语种：英文

外文关键词：endoscopic resection; extramedullary plasmacytoma; gastric plasmacytoma; immunohistochemistry; pathological diagnosis; solitary plasmacytoma

摘要：Extramedullary plasmacytoma (EMP) is a rare plasma cell malignancy, accounting for approximately 3% of all plasma cell neoplasms. Gastric plasmacytoma, a distinct subtype of EMP arising from B lymphocytes, is extremely uncommon, representing roughly 2% of EMP cases, and lacks specific clinical manifestations. Herein, we report a 53-year-old male presenting with persistent acid reflux and heartburn. Gastroscopy identified a flat, elevated lesion in the gastric body. Endoscopic mucosal resection (EMR) was performed to obtain the lesion specimen. The diagnosis of primary solitary gastric plasmacytoma was confirmed via histopathology, immunohistochemistry, bone marrow aspiration, serum and urine free light chain assays, and positron emission tomography-computed tomography (PET-CT). We further review the clinical features, diagnostic approaches, therapeutic strategies, and prognosis of this disease, aiming to provide a reference for the diagnosis and management of rare gastric plasma cell tumors in clinical practice.