文献类型：期刊文献

中文题名：当归平衡脱水干燥工艺优化

英文题名：Balanced dehydration drying process optimization for Angelica sinensis

作者：荔淑楠[1];王引权[1,2];马丽丽[3];彭桐[1];傅金魁[3];李淑琪[1]

第一作者：荔淑楠

机构：[1]甘肃中医药大学药学院,甘肃兰州730000;[2]甘肃省中药质量与标准研究重点实验室培育基地,甘肃兰州730000;[3]北京华珍烘烤系统设备工程有限公司工艺部,北京100029

第一机构：甘肃中医药大学药学院（西北中藏药协同创新中心办公室）

年份：2020

卷号：42

期号：3

起止页码：681

中文期刊名：中成药

外文期刊名：Chinese Traditional Patent Medicine

收录：CSTPCD;;北大核心:【北大核心2017】；CSCD:【CSCD2019_2020】；

基金：国家自然科学基金项目(81660625,81260616);国家重点研发计划(2017YFC1700705);甘肃省高校协同创新科技团队支持计划(2016C-05FF09)。

语种：中文

中文关键词：当归;平衡脱水干燥;外观性状;正交试验

外文关键词：Angelica sinensis(Oliv.)Diels;balance dehydration drying;appearance characteristic;orthogonal test

摘要：目的优化当归平衡脱水干燥工艺。方法以干燥温度、干燥湿度、缓苏时间、干燥时间为影响因素,正交试验优化平衡脱水干燥工艺;以外观性状、显微、薄层色谱法结合挥发油提取率、醇溶性浸出物、多糖、阿魏酸和5种苯肽类成分为考察指标,并与药典工艺对比,综合评价不同干燥工艺参数对当归药材品质的影响。结果最佳平衡脱水干燥工艺为干燥温度50℃,干燥湿度50%,缓苏12 h,干燥36 h;2种不同的平衡脱水干燥工艺均优于药典工艺,外观性状及显微特征均较一致。结论该方法稳定可行,可用于当归的平衡脱水干燥。
AIM To optimize the balanced dehydration drying process of Angelica sinensis(Oliv.)Diels.METHODS With drying temperature, drying humidity, tempering time and drying time as influencing factors,the balanced dehydration drying process was optimized by orthogonal test.The appearance, microscopic and thin layer chromatography were used, and combined with the extraction rate of volatile oil, alcohol-soluble extracts, polysaccharides, ferulic acid and five kinds of phthalides. Meanwhile, they were compared with the method in Pharmacopoeia to evaluate the effects of different drying parameters on the quality of A. sinensis.RESULTS The optimal balanced dehydration drying process conditions were determined to be 50 ℃for drying temperature,50% for drying humidity,12 h for tempering time,36 h for tempering time. Compared with the process stipulated in the Chinese Pharmacopoeia, both of the two balanced dehydration drying processes were superior, and the appearance and microscopic characteristics were consistent.CONCLUSION This stable and feasible method can be used for the balanced dehydration drying process of A. sinensis.