文献类型：期刊文献

中文题名：高强度间歇训练与中等强度持续训练对冠心病患者影响的Meta分析

英文题名：Meta-analysis of the clinical efficacy of high-intensity interval exercise and middle-intensity continuous training in patients with coronary heart disease

作者：胡玉洁[1];谢萍[1,2];卢维杰[3];杨康[3];邓耀庭[3];刘梦洋[3]

第一作者：胡玉洁

机构：[1]兰州大学第一临床医学院,甘肃省兰州市730000;[2]甘肃省人民医院,甘肃省兰州市730000;[3]甘肃中医药大学,甘肃省兰州市730000

第一机构：兰州大学第一临床医学院,甘肃省兰州市730000

年份：2026

卷号：30

期号：10

起止页码：2584

中文期刊名：中国组织工程研究

外文期刊名：Chinese Journal of Tissue Engineering Research

收录：;北大核心:【北大核心2023】；

基金：甘肃中医药大学创新创业项目(2025CXZX-917),项目负责人:卢维杰。

语种：中文

中文关键词：冠心病;高强度间歇训练;中等强度持续训练;心脏康复;临床疗效;随机对照研究;Meta分析

外文关键词：coronary heart disease;high-intensity interval exercise;moderate-intensity aerobic exercise;cardiac rehabilitation;clinical efficacy;randomized controlled trial;meta-analysis

摘要：目的:研究表明,高强度间歇训练在改善冠心病患者心肺功能方面可能优于中等强度持续训练,但高强度间歇训练的临床疗效仍存在争议。此次研究旨在系统评估高强度间歇训练与中等强度持续训练对冠心病患者临床疗效的影响。方法:通过检索中国知网、万方数据库、维普数据库、PubMed、Cochrane Library、Embase、Web of Science等数据库,选择高强度间歇训练、中等强度持续训练应用于冠心病心脏康复有关的随机对照试验,使用Review Manager 5.3及Stata MP 17软件对最终纳入的文献进行Meta分析。结果:共纳入10篇文献,包括786例患者。Meta分析结果显示,高强度间歇训练组峰值摄氧量、第一通气阈时摄氧量均高于中等强度持续训练组[MD=1.30,95%CI(0.71,1.89),P<0.0001;MD=1.54,95%CI(0.56,2.53),P=0.002],两组间静息心率、峰值心率、静息收缩压与静息舒张压比较差异均无显著性意义(P>0.05)。结论:相较于中等强度持续训练,高强度间歇训练在改善冠心病患者峰值摄氧量及第一通气阈时摄氧量方面更有优势,而对静息心率、峰值心率、静息收缩压、静息舒张压无明显影响。
OBJECTIVE:Although existing studies have suggested that high-intensity interval training may be more effective than moderate-intensity continuous training in improving cardiopulmonary function in patients with coronary heart disease,its clinical efficacy remains controversial.Therefore,this meta-analysis aims to systematically evaluate the clinical efficacy of high-intensity interval training versus moderate-intensity continuous training in patients with coronary heart disease.METHODS:Randomized controlled trials of high-intensity interval training and moderate-intensity continuous training in cardiac rehabilitation of coronary heart disease were included by searching Chinese and English databases such as CNKI,WanFang Database,Wipro,PubMed,Cochrane Library,Embase,and Web of science.Meta-analysis of the final included literature was performed using Review Manager 5.3 and StataMP 17.RESULTS:A total of 10 studies met the study criteria and included 773 patients.Compared with moderate-intensity continuous training,high-intensity interval training resulted in higher peak oxygen uptake and oxygen uptake at the first ventilatory threshold were higher[mean difference=1.30,95%confidence interval(0.71,1.89),P<0.0001;mean difference=1.54,95%confidence interval(0.56,2.53),P=0.002].Both groups showed no significant difference in resting systolic blood pressure,resting diastolic blood pressure,resting heart rate and peak heart rate(P>0.05).CONCLUSION:Compared with moderate-intensity continuous training,high-intensity interval training is more advantageous in improving peak oxygen uptake and oxygen uptake at the first ventilation threshold in coronary artery disease,while has no significant effects on resting heart rate,peak heart rate,resting systolic blood pressure,and resting diastolic blood pressure.