文献类型：期刊文献

英文题名：Prevalence and Determinants of Delay in Time-to-Diagnosis for Pulmonary Arterial Hypertension Patients in Gansu China: A Observational Cohort Study

作者：Zhang, Juxia[1];Meng, Hongyan[2];Yin, Yuhuan[3];Zhang, Yiyin[2];Wen, Yujie[4];Zhang, Rong[2];Wang, Jiancheng[5]

第一作者：Zhang, Juxia

通信作者：Wang, JC[1]

机构：[1]Gansu Prov Hosp, Clin Educ Dept, Lanzhou, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Sch Nursing, Lanzhou, Gansu, Peoples R China;[3]Air Force Med Univ, Affiliated Hosp 2, Dept Thorac Surg, Xian, Peoples R China;[4]Gansu Prov Hosp, Dept Cardiol, Lanzhou, Gansu, Peoples R China;[5]Hosp Gansu Hlth Vocat Coll, Dept Gen Practice Med, Lanzhou 730000, Gansu, Peoples R China

第一机构：Gansu Prov Hosp, Clin Educ Dept, Lanzhou, Gansu, Peoples R China

通信机构：[1]corresponding author), Hosp Gansu Hlth Vocat Coll, Dept Gen Practice Med, Lanzhou 730000, Gansu, Peoples R China.

年份：2023

卷号：48

期号：12

外文期刊名：CURRENT PROBLEMS IN CARDIOLOGY

收录：;Scopus(收录号：2-s2.0-85168455575);WOS:【SCI-EXPANDED(收录号:WOS:001067744800001)】；

基金：Funding: This study was supported by the National Natural Science Foundation of China (72264002) , the China Medical Education Association Project (2022KTZ010) , the Natural Science Foundation of Gansu Province (21JR7RA607 and 21JR7RA613) , the Health Industry Research Plan Project of Gansu Province (GSWSKY-2019-50) , and Research Fund project of Gansu Provincial Hospital (22GSSYYD-70) .

语种：英文

摘要：Current studies of patients with pulmonary arterial hypertension (PAH) have shown a significant diagnostic delay. However, the causes and risk factors for this delay are not been well explored in Chinese population. This study aimed to assess the status of diagnostic delay in patients with PAH in China. Additionally, we identified factors associated with the delay. Demographic and clinical data were collected from 153 PAH patients admitted to three tertiary hospitals in Gansu, China, from March 2020 to October 2022. Based on the recorded date, the diagnostic delay was divided into patient delay and health system delay. For analysis, we divided diagnostic delay into 2 groups (= 3 years and >3 years). Factors associated with delay were identified by binary logistic regression. The median diagnostic delay was 3 years (IQR: 0.25-5.88). Binary logistic regression analysis showed that male (OR = 2.48, 95% CI: 1.10-5.58), those with junior high school or below (OR = 3.65, 95% CI: 1.36-9.78), living far away from the tertiary hospital (OR = 2.66, 95% CI: 1.14-6.18), initially visit hospital before 2018 (OR = 3.82, 95% CI: 1.68-8.71), and visit hospital at county level or below (OR = 3.80, 95% CI: 1.42-10.18) were risk factor for diagnostic delay (>3 years). Despite increased awareness, most patients with PAH in Gansu, China still experienced a delay in diagnosis of more than 3 years. Male sex, lower educational background, and being away from tertiary hospitals are risk factors for delay. Furthermore, factors impacting time-to-diagnosis and its impact should be continuously evaluated as therapeutic strategies continue to evolve and improve. (Curr Probl Cardiol 2023;48:102026.)