文献类型：期刊文献

中文题名：温通针法减轻脑缺血损伤的实验研究——对脑缺血再灌注大鼠脑组织Ca及Mg元素含量的影响

英文题名：Influence of Warming-promotion Method of Acupuncture on the Contents of the Elements Ca and Mg in Brain Tissue of Rats with Cerebral Ischemia and Reperfusion

作者：梁宪如[1];郭永明[2];郑俊江[3];郑俊朋[3];严兴科[3];郑魁山[4]

第一作者：梁宪如

机构：[1]武警医学院附属医院,天津,300162;[2]天津中医学院,天津,300193;[3]甘肃郑氏针法研究会,甘肃兰州,730000;[4]甘肃中医学院,甘肃兰州,730000;

第一机构：武警医学院附属医院,天津,300162

年份：2002

卷号：19

期号：3

起止页码：30

中文期刊名：天津中医

外文期刊名：Tianjin Journal of Traditional Chinese Medicine

基金：甘肃省科学技术攻关项目 (课题号GS992 -A43 -064)

语种：中文

中文关键词：脑缺血;再灌注;温通针法;钙;镁;实验研究;针灸疗法

外文关键词：Cerebral ischemia and reperfusion; Rat; Ca; Mg; Warming-promotion method of acupuncture

摘要：目的 :观察温通针法治疗脑缺血的作用机理。方法 :用改良的四血管结扎法造成大鼠脑缺血及再灌注模型 ,观察脑组织Ca及Mg元素、脑组织含水量的变化及温通针法的干预效应。结果 :脑缺血再灌注后再灌组脑组织Ca元素及含水量显著增高(P<0.01) ,而Mg元素含量显著降低(P<0.01) ,用温通针法治疗后脑组织含水量、Ca元素含量明显降低(P<0.01) ,Mg元素明显升高(P<0.01)。结论 :提示该针法具有明显减轻脑水肿 ,使再灌注脑组织Ca元素含量降低 ,Mg 元素含量升高 ,从而减轻再灌注损伤的作用。
Objective: To observe the effects of warming-promotion method of acupuncture on the contents of the elements Ca and Mg in brain tissue of rats with cerebral ischemia and reperfusion (I/R) injury. Methods: The contents of Ca, Mg and water in rats' brain and the curative effect were observed in experimental model of I/R induced by modified method of 4- vessel ligation. Results: The H2O and Ca content in the brain tissue increased significantly(P<0.01)while the Mg content decreased significantly (P<0.01)when compared with those in control group. After treating with the warming-promotion method of acupuncture, the H2O and Ca content in the brain tissue decreased significantly while the Mg content increased significantly when compared with model group(P<0.01). Conclusion: It suggests that the warming-promoting method of acupuncture can reduce the severity of the injury of cerebral I/R.