文献类型：期刊文献

英文题名：Synthesis of Se polysaccharide catalyzed by sulfonic acid functionalized ionic liquids: Synergism effect of anion/cation

作者：Wei, Zhangkun[1];Guo, Duoduo[1];He, Jianhua[1];Liu, Xiaoxiao[1,2];Wei, Yabing[1];Bao, Aijuan[1];Jin, Xiaojie[3];Kong, Weibao[1,4];Zhang, Ji[1,4];Wang, Junlong[1,4]

第一作者：Wei, Zhangkun

通信作者：Wang, JL[1]

机构：[1]Northwest Normal Univ, Coll Life Sci, Anning Eastroad 967, Lanzhou 730070, Peoples R China;[2]Lanzhou Inst Food & Drug Control, Lanzhou 730050, Peoples R China;[3]Gansu Univ Chinese Med, Coll Pharm, Lanzhou 730030, Peoples R China;[4]Northwest Normal Univ, Inst New Rural Dev, Lanzhou 730070, Peoples R China

第一机构：Northwest Normal Univ, Coll Life Sci, Anning Eastroad 967, Lanzhou 730070, Peoples R China

通信机构：[1]corresponding author), Northwest Normal Univ, Coll Life Sci, Anning Eastroad 967, Lanzhou 730070, Peoples R China.

年份：2023

卷号：245

外文期刊名：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

收录：;EI(收录号：20232614305872);Scopus(收录号：2-s2.0-85162902485);WOS:【SCI-EXPANDED(收录号:WOS:001037261100001)】；

基金：The present work is supported by the following funds: Science Fund for Distinguished Young Scholars of Gansu Province (17JR5RA067) , Gansu Education Department (CN) (2020C-21) , Excellent Doctoral Candidates Project of Gansu Province (22JR5RA135) , Gansu Excellent Postgraduate "Innovation Star" Project (2021CXZX-213, 2022CXZX- 252) .

语种：英文

外文关键词：Se-functionalization; Sulfonic acid functionalized ionic liquids & nbsp; catalyst; Synergism effect of anion; cation

摘要：The rational design and construction of controllable selenylation strategy are important for the study on the structure-activity relationship of Se polysaccharides. Herein, selenized Artemisia sphaerocephala polysaccharides (SePASs) were synthesized by using sulfonic acid functionalized ionic liquids (SFILs) as catalysts in order to study the regulation of the cation/anion constitute on the selenylation efficiency and Se polysaccharide structure. Impressively, SFILs could promote the efficient substitution of seleno-group on the polysaccharide backbone through the synergistic catalysis by cation/anions (Se content up to 5582.7 & mu;g/g). Further, reaction mechanism and potential dissolution effect was supported by DFT calculation and polarized light microscopy. 13C NMR and FT-IR spectra analysis of SePASs exhibited that selenite existed in polysaccharides and the substitution position occured at C-6. SEC-MALLS, monosaccharide composition results revealed that strong acidity of SFILs lead to the driving forces toward low molecular mass polysaccharide fragments and synergistic effect of anion/cations in SFILs (-SO3H group of cations as proton donor, anions as nucleophile) showed regulation on average molecular mass. In addition, the strong attractions between the seleno-groups generated agglomeration of polysaccharide chain, which was proved by applying AFM analysis. Therefore, this work provided a new insight for manipulate Se content and MW of Se polysaccharides.