文献类型：期刊文献

英文题名：Trends of High-Impact Studies in Pharmacology and Pharmacy: A Cross-Sectional Study

作者：Chen, Lingmin[1,2,3];Yang, Yi[4];Fan, Jin[5];Zhang, Yonggang[2,6,7];Li, Nian[8]

第一作者：Chen, Lingmin

通信作者：Li, NA[1]

机构：[1]Sichuan Univ, Dept Anesthesiol, West China Hosp, Chengdu, Peoples R China;[2]Sichuan Univ, Natl Clin Res Ctr Geriatr, West China Hosp, Chengdu, Peoples R China;[3]Chinese Acad Med Sci, Res Units West China 2018RU012, Chengdu, Peoples R China;[4]Gansu Univ Tradit Chinese Med, Dept Clin Med, Lanzhou, Peoples R China;[5]Chengdu Univ Tradit Chinese Med, Sch Hlth Preservat & Rehabil, Lanzhou, Peoples R China;[6]Sichuan Univ, West China Hosp, Chinese Evidence Based Med Ctr, Chengdu, Peoples R China;[7]Sichuan Univ, West China Hosp, Dept Period Press, Chengdu, Peoples R China;[8]Sichuan Univ, West China Hosp, Dept Med Adm, Chengdu, Peoples R China

第一机构：Sichuan Univ, Dept Anesthesiol, West China Hosp, Chengdu, Peoples R China

通信机构：[1]corresponding author), Sichuan Univ, West China Hosp, Dept Med Adm, Chengdu, Peoples R China.

年份：2021

卷号：12

外文期刊名：FRONTIERS IN PHARMACOLOGY

收录：;Scopus(收录号：2-s2.0-85116190979);WOS:【SCI-EXPANDED(收录号:WOS:000702017800001)】；

基金：This study is partly supported by the Science and Technology Department of Sichuan Province (No: 2020YFS0186), China Postdoctoral Science Foundation (No: 2021M692274), The Post-Doctor Research Project of West China Hospital of Sichuan University (No. 19HXBH071), National Natural Science Foundation of China (No: 82001130). This study is edited by Enliven

语种：英文

外文关键词：high-impact studies; pharmacology and pharmacy research; visual analysis; cancer; InCites; Web of Science

摘要：Objective: To investigate the trends of high-impact studies in pharmacology and pharmacy research and to provide evidence for future research in the field of pharmacology and pharmacy.

Methods: A cross-sectional study was performed to understand the current status of high-impact studies (top 1%) in pharmacology and pharmacy research via InCites tool based on Web of Science Core Collection. VOSViewer software was used to visualize the results. The outcomes included development trends, countries, subject areas, research institutes, collaborative networks, and subject terms.

Results: We found 4,273 high-impact (top 1%) studies between 2011 and 2020 in the field of pharmacology and pharmacy. The number of studies increased from 366 in 2011 to 510 in 2020. These studies were mainly distributed in the following Web of Science subject categories: pharmacology and pharmacy (n = 4,188); neurosciences (n = 397); chemistry, multidisciplinary (n = 359); chemistry, medicinal (n = 314); microbiology (n = 301); biotechnology and applied microbiology (n = 280). These studies were cited in 646,855 studies from more than 100 Web of Science subject categories, and studies in pharmacology pharmacy accounted for the largest share of these citations. The top three countries that contributed the highest number of studies were the United States, United Kingdom, and China. The top three institutions that contributed the highest number of studies in the United States were the University of California System, the National Institutes of Health (NIH), and Harvard University. The top research collaborative circle was from universities in the United States. The top international collaborative circle was from universities from the United States, United Kingdom, Australia, and China. The subject-term analysis indicated that cancer was still the top disease, NF-kappa B was the top signaling pathway, and drug-delivery and nanoparticles were the top methods.

Conclusion: The high-impact studies in pharmacology and pharmacy research have grown over time. The United States, the United Kingdom, and China are the top countries that contributed the high-impact studies. Cancer is still the greatest challenge in the field of disease treatment. It calls for more international collaboration in pharmacology and pharmacy research, which will help discover novel drugs.