文献类型：期刊文献

中文题名：薏苡仁油-羟丙基-β-环糊精包合物制备工艺研究

英文题名：Study on Preparation Process of Inclusion Compound of Coix Seed Oil with Hydroxypropyl β-Cyclodextrin

作者：汪付田[1];靳子明[2];郭敏[1]

第一作者：汪付田

机构：[1]甘肃省中医院,甘肃兰州730050;[2]甘肃中医学院附属医院,甘肃兰州730000

第一机构：甘肃省中医院,甘肃兰州730050

年份：2010

卷号：17

期号：10

起止页码：56

中文期刊名：中国中医药信息杂志

外文期刊名：Chinese Journal of Information on Traditional Chinese Medicine

收录：CSTPCD;;CSCD:【CSCD_E2011_2012】；

语种：中文

中文关键词：薏苡仁油;羟丙基-β-环糊精;包合物;制备工艺

外文关键词：Coix seed oil; hydroxypropyl-β-cyclodextrin： inclusion compound~ preparation process

摘要：目的制备薏苡仁油-羟丙基-β-环糊精包合物并对其加以鉴定。方法采用冷冻干燥法制备薏苡仁油-羟丙基-β-环糊精包合物。结果经薄层色谱、差示扫描量热分析等方法对包合物鉴定,表明薏苡仁油-羟丙基-β-环糊精已形成包合物。结论薏苡仁油脂经羟丙基-β-环糊精包合后溶解度可明显提高。
Objective To prepare the inclusion compound of Coix seed oil and Hydroxypropyl-β-Cyclodextrin （HP-β--CD） and identify it. Methods The inclusion compound of Coix seed oil-β-CD was prepared by freeze drying method. Results TLC spectronscopy and differentieal scanning calorimetry （DSC） indicated that the inclusion compound of Coix seed oil-HP-β-CD was formed. Conclusion The solubility of Coix seed oil was increased when the drug is included by HP-β-CD.