文献类型：期刊文献

中文题名：高血压病合并糖尿病患者的中医证型与胱抑素C的相关性研究

英文题名：A correlativity study of TCM syndrome and cystatin C in hypertension patients with diabetes

作者：寇宗莉[1];徐鑫[1];杨开燕[1];王记[1];李淑玲[1]

第一作者：寇宗莉

机构：[1]甘肃中医药大学附属医院,甘肃兰州730000

第一机构：甘肃中医药大学第二附属医院

年份：2021

卷号：13

期号：20

起止页码：18

中文期刊名：中医临床研究

外文期刊名：Clinical Journal Of Chinese Medicine

基金：甘肃省中医药管理局科技项目(GZK-2014-51)。

语种：中文

中文关键词：高血压病合并糖尿病;中医证型;胱抑素C

外文关键词：Hypertension with diabetes;TCM syndrome;Cystatin C

摘要：目的:探讨高血压病合并糖尿病患者的中医证型与胱抑素C的相关性。方法:收集2015年1月-2016年9月在甘肃中医药大学附属医院的门诊及住院的高血压病合并糖尿病患者250例,收集其一般病理资料与临床资料。根据中医证型对高血压病合并糖尿病患者进行分型,评估不同中医证型高血压病合并糖尿病患者在不同中医证型中的病例数及构成比率。评估高血压病合并糖尿病患者不同中医证型之间的胱抑素C、尿素氮、肌酐和尿酸的差异性。结果:根据中医证型,对纳入研究的250例入组患者分为肝火亢盛、肝肾两虚、气阴两虚和痰瘀互结4种中医证型。不同中医证型的构成比率从大到小依次为:痰瘀互结组>气阴两虚组>肝肾亏虚组>肝火亢盛组。高血压病合并糖尿病患者不同中医证型的胱抑素C、尿素氮、肌酐、尿酸对比差异均有统计学意义(P<0.05)。结论:高血压病合并糖尿病患者的不同中医证型与血清胱抑素C具有相关性,为指导临床早期干预,减少肾损害的发生提供了一定的理论依据。
Objective:To investigate the relationship between TCM syndromes and cystatin C in patients with hypertension complicated with diabetes.Methods:250 patients with hypertension and diabetes in the outpatient and inpatient clinics of Affilicated Hospital of Gansu University of Chinese Medicinefrom January 2015 to September 2016 were collected,and their general pathological and clinical data were collected.According to the TCM syndrome type,the patients with hypertension and diabetes were classified,and the number of cases and the composition ratio of the patients with different TCM syndromes and diabetes in different TCM syndrome types were evaluated.The differences in cystatin C,urea nitrogen,creatinine and uric acid among different TCM syndromes were evaluated in patients with hypertension and diabetes.Results:According to TCM syndrome types,the 250 patients with hypertension and diabetes included in the study were divided into four TCM syndrome types:hyperactivity of liver and fire,deficiency of both liver and kidney,deficiency of both Qi(气)and Yin(阴),and mutual accumulation of phlegm and blood stasis.The composition ratios of different TCM syndrome types in descending order:liver and kidney deficiency group>phlegm and blood stasis group>liver and fire hyperactivity group>qi and Yin deficiency group.There were statistically significant differences in cystatin C,urea nitrogen,creatinine,and uric acid in patients with hypertension and diabetes with different TCM syndromes(P<0.05).Conclusion:The different TCM syndromes of patients with hypertension and diabetes were related to serum cystatin C.