文献类型：期刊文献

英文题名：Highly flexible and stretchable silk composite films with manipulated hierarchical hydrogen bonds for on-skin electronics

作者：Zhang, Cuiling[1];Wang, Yijing[1];Yang, Yongze[1];Tian, Jingyu[1];Zhan, Wang[1];Li, Changjiang[2];Zhang, Qi[1,3];Zhao, Jingye[1];Zhang, Yue[2];Peng, Niancai[4];Li, Ping[5];Zhang, Xiaohui[1]

第一作者：Zhang, Cuiling

通信作者：Zhang, XH[1];Li, P[2]

机构：[1]Xi An Jiao Tong Univ, Ctr Mitochondrial Biol & Med,Minist Educ,Int Joint, State Ind Educ Integrat Ctr Med Innovat,Key Lab Bi, Sch Life Sci & Technol,State Key Lab Mfg Syst Engn, Xian 710049, Shaanxi, Peoples R China;[2]Xi An Jiao Tong Univ, Univ Shaanxi Prov, Engn Res Ctr Spin Quantum Sensor Chips,Key Lab,Min, Sch Elect Sci & Engn,State Key Lab Mfg Syst Engn,E, Xian 710049, Peoples R China;[3]Gansu Univ Chinese Med, Sch Med Informat Engn, Lanzhou 730000, Peoples R China;[4]Xi An Jiao Tong Univ, Int Joint Lab Micro Nano Mfg & Measurement Technol, Xian Key Lab Biomed Testing & High End Equipment, State Key Lab Mfg Syst Engn,Sch Instrument Sci & T, Xian 710054, Peoples R China;[5]Xi An Jiao Tong Univ, Sch Mat Sci & Engn, State Key Lab Mech Behav Mat, Xian 710049, Peoples R China

第一机构：Xi An Jiao Tong Univ, Ctr Mitochondrial Biol & Med,Minist Educ,Int Joint, State Ind Educ Integrat Ctr Med Innovat,Key Lab Bi, Sch Life Sci & Technol,State Key Lab Mfg Syst Engn, Xian 710049, Shaanxi, Peoples R China

通信机构：[1]corresponding author), Xi An Jiao Tong Univ, Ctr Mitochondrial Biol & Med,Minist Educ,Int Joint, State Ind Educ Integrat Ctr Med Innovat,Key Lab Bi, Sch Life Sci & Technol,State Key Lab Mfg Syst Engn, Xian 710049, Shaanxi, Peoples R China;[2]corresponding author), Xi An Jiao Tong Univ, Sch Mat Sci & Engn, State Key Lab Mech Behav Mat, Xian 710049, Peoples R China.

年份：2026

卷号：381

外文期刊名：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

收录：;EI(收录号：20263521365994);Scopus(收录号：2-s2.0-105048232905);WOS:【SCI-EXPANDED(收录号:WOS:001862660100001)】；

基金：We thank Jia Liu and Chang Huang at the Instrumental Analysis Center of Xi'an Jiaotong University for their assistance with Raman and XRD analysis assistance. This work was financially supported by the National Key Research and Development Program of China (2022YFB3206805HZ) and the counterpart project (GXKJXM20230186) .

语种：英文

外文关键词：Flexibility; Silk composite film; Hydrogen bond; Hierarchical structure; Physiological monitoring

摘要：As the rapid evolution of modern electronics, wearable electronics that can non-invasively capture signal have attracted increasing attention in healthcare system. The ideal wearable electronics for healthcare should to be on-skin electronics with mechanical compliance and biocompatibility. Inspired by its natural biocompatibility, silk is elected to integrate with wearable electronics. However, its inherent stiffness and brittleness restrict on-skin applications. In this work, we present flexible silk composite films (SCFs) with lower binding energy through disrupting the ordered hydrogen (H) bonds in silk for on-skin electronics. Waterborne polyurethane and bis(2-hydroxyethyl) disulfide are incorporated to manipulate the H bonds which modulates the hierarchical structural transitions of silk, thus softening the SCF. The resulting SCF demonstrates markedly improved stretchability (similar to 97.30%) and reduced elastic modulus (similar to 37.85 MPa), representing a 1796.69% increase and a 98.15% reduction, respectively, compared to pure silk films. Benefiting from these improved mechanical properties, the SCFs are employed as electrodes for capturing electromyogram (EMG) and electrocardiogram (ECG) signals. Furthermore, a pressure sensor is constructed by integrating the SCF electrodes with a micro-structured SCF layer, which exhibits a wide sensing range (0-200.8 kPa) with an impressive sensitivity of 0.493 kPa(-1)in the range of 0-12 kPa and a rapid response time of 120 ms. Therefore, the sensor enables reliable monitoring of various physiological signals, including pulse, swallowing, respiration, and writing of English letters. This study provides a new avenue for developing flexible silk-based films and expands their application in advanced wearable bioelectronics.