文献类型：期刊文献

英文题名：Chemical composition, biological activities, and quality standards of hawthorn leaves used in traditional Chinese medicine: a comprehensive review

作者：Guo, Wenjing[1,2];Shao, Tingting[1];Peng, Yu[3];Wang, Haitao[2];Chen, Zhe-Sheng[4];Su, Haixiang[2]

第一作者：Guo, Wenjing;郭文静

通信作者：Su, HX[1];Chen, ZS[2]

机构：[1]Gansu Univ Chinese Med, Lanzhou, Peoples R China;[2]Gansu Prov Canc Hosp, Gansu Prov Acad Inst Med Res, Lanzhou, Peoples R China;[3]Lanzhou Univ, Hosp 1, Lanzhou, Peoples R China;[4]St Johns Univ, Coll Pharm & Hlth Sci, Dept Pharmaceut Sci, Queens, NY 11432 USA

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Prov Canc Hosp, Gansu Prov Acad Inst Med Res, Lanzhou, Peoples R China;[2]corresponding author), St Johns Univ, Coll Pharm & Hlth Sci, Dept Pharmaceut Sci, Queens, NY 11432 USA.

年份：2023

卷号：14

外文期刊名：FRONTIERS IN PHARMACOLOGY

收录：;Scopus(收录号：2-s2.0-85175841132);WOS:【SCI-EXPANDED(收录号:WOS:001092374800001)】；

基金：Thanks for the hard work of each author.r The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Lanzhou Talent Innovation and Entrepreneurship Project (2017-RC-27), Gansu Provincial Science and Technology Plan Project (22JR11RA125), the Open Project of Gansu Traditional Chinese Medicine Research Center (zyzx-2020-zxl), the Open Fund for Research and Promotion of Quality Standardization Technology for Genuine Medicinal Materials in Gansu Province (ddyc-2022-05).

语种：英文

外文关键词：hawthorn leaves; chemical composition; quality standard; biological activity; traditional Chinese medicine

摘要：Hawthorn leaves also known as crataegi foilum, are a combination of botanical drugs used commonly in Traditional Chinese Medicine. Hawthorn, the plant from which hawthorn leaves are prepared, is distributed in Northeast China, North China, and other regions in China. Hawthorn leaves are known to activate blood circulation and eliminate stasis, invigorating Qi, eliminating turbidity, and reducing the levels of lipids. So far, over a hundred compounds have been isolated from hawthorn leaves, including flavonoids, terpenoids, lignans, organic acids, and nitrogenous compounds. Hawthorn leaves are used for the treatment of hypertension, protecting against ischemic injury, angina, hyperglycemia, hyperlipidemia, and certain other conditions. Several of the currently available clinical preparations also use hawthorn leaves as raw materials, such as Yixintong capsules, Xinan capsules, etc. The present report systematically reviews the chemical composition, biological activities, and quality standards of hawthorn leaves, to provide a scientific basis and reference for detailed research on hawthorn leaves.