文献类型：期刊文献

英文题名：Effect evaluation of different preventive measures for ileus after abdominal operation: A systematic review and network meta-analysis

作者：Cui, Yan[1,4,5];Zhang, Chengzu[1];Zhang, Hui[1];Zhang, Xuan[1];Tang, Yuan[1];Wu, Zhihang[1];Wang, Tianming[1];Chen, Quanxin[1];Meng, Ying[2];Wang, Bo[3];Liu, Mei[1,6];Yi, Jianfeng[1];Shi, Yuhong[1];Li, Richeng[1];Pan, Haibang[1]

第一作者：Cui, Yan

通信作者：Pan, HB[1];Wang, B[2]

机构：[1]Gansu Univ Chinese Med, Sch Clin Med 1, Lanzhou, Gansu, Peoples R China;[2]Expo High tech Hosp, Dept Pharm, Zibo, Shandong, Peoples R China;[3]Gansu Univ Chinese Med, Sch Nursing, Lanzhou, Gansu, Peoples R China;[4]Gansu Univ Chinese Med, Key Lab Gansu Prov Prescript Min, Lanzhou 730000, Gansu, Peoples R China;[5]Gansu Univ Chinese Med, Innovat Translat Lab, Lanzhou 730000, Gansu, Peoples R China;[6]Gansu Univ Chinese Med, Gansu Prov Tradit Chinese Med New Prod Creat Engn, Lanzhou 730000, Gansu, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Sch Clin Med 1, Lanzhou, Gansu, Peoples R China;[2]corresponding author), Gansu Univ Chinese Med, Sch Nursing, Lanzhou, Gansu, Peoples R China.|[107352f23a9081f8152fc]甘肃中医药大学护理学院;[10735]甘肃中医药大学;

年份：2024

卷号：10

期号：4

外文期刊名：HELIYON

收录：;Scopus(收录号：2-s2.0-85184571985);WOS:【SCI-EXPANDED(收录号:WOS:001184356800001)】；

基金：Funding statement This study received funding from the National Natural Science Foundation of China (81860850) , Gansu Education Department (2023A-076) , and Lanzhou City Science and Technology Bureau (2020-XG-26)

语种：英文

外文关键词：Abdominal surgery; Ileus; Prevention; Network meta -analysis

摘要：Background: Different approaches to the prevention of postoperative ileus have been evaluated in numerous randomized controlled trials. This network meta-analysis aimed to investigate the relative effectiveness of different interventions in preventing postoperative ileus. Methods: Randomized controlled trials (RCTS) on the prevention of postoperative ileus were screened from Chinese and foreign medical databases and compared. STATA software was used for network meta-analysis using the frequency method. Random-effects network meta-analysis was also used to compare all schemes directly and indirectly. Results: A total of 105 randomized controlled trials with 18,840 participants were included in this report. The results of the network meta-analysis showed that intravenous analgesia was most effective in preventing the incidence of postoperative ileus, the surface under the cumulative ranking curve (SUCRA) is 90.5. The most effective intervention for reducing the first postoperative exhaust time was postoperative abdominal mechanical massage (SUCRA: 97.3), and the most effective intervention for reducing the first postoperative defecation time was high-dose opioid antagonists (SUCRA: 84.3). Additionally, the most effective intervention for reducing the time to initiate a normal diet after surgery was accelerated rehabilitation (SUCRA: 85.4). A comprehensive analysis demonstrated the effectiveness and prominence of oral opioid antagonists and electroacupuncture (EA) combined with gum. Conclusion: This network meta-analysis determined that oral opioid antagonists and EA combined with chewing gum are the most effective treatments and optimal interventions for reducing the incidence of postoperative ileus. However, methods such as abdominal mechanical massage and coffee require further high-quality research.