文献类型：期刊文献

中文题名：内脏型肥胖对右半结肠癌术后早期并发症的影响

英文题名：Effect of visceral obesity on early postoperative complications of right colon cancer

作者：赵丽霞[1,2];曹聪[2,3];张洪来[2,3];陈一锋[2,3];王涛[2,3];张维胜[2,3];杨熊飞[2,3]

第一作者：赵丽霞

机构：[1]甘肃中医药大学第一临床医学院,甘肃兰州730000;[2]甘肃省肛肠疾病临床医学研究中心,甘肃兰州730000;[3]甘肃省人民医院肛肠科,甘肃兰州730000

第一机构：甘肃中医药大学临床医学院

年份：2023

卷号：31

期号：10

起止页码：1865

中文期刊名：现代肿瘤医学

外文期刊名：Journal of Modern Oncology

收录：CSTPCD;;北大核心:【北大核心2020】；

基金：甘肃省自然科学基金(编号:22JR5RA676);甘肃省肛肠疾病临床医学研究中心项目(编号:20JR10RA434);甘肃省人民医院院内科研基金(编号:21GSSYC-19)。

语种：中文

中文关键词：内脏型肥胖;VFA;右半结肠癌;术后早期并发症

外文关键词：visceral obesity;VFA;right colon cancer;early postoperative complications

摘要：目的:探究内脏型肥胖对右半结肠癌根治术后早期并发症的影响。方法:回顾性分析2020年10月至2022年10月在甘肃省人民医院肛肠科接受右半结肠癌根治性手术治疗患者的临床病理资料。依据患者术前1个月内的腹部CT资料,估计内脏脂肪面积(visceral fat area, VFA),将VFA≥100 cm^(2)归为VFA-H组,VFA<100 cm^(2)归为VFA-L组。比较两组患者的临床病理特征和术后早期并发症情况。采用单因素及多因素Logistic回归模型,分析影响右半结肠癌术后早期并发症发生的危险因素。结果:共纳入112例右半结肠癌患者,其中VFA-H组共49例,VFA-L组共63例。两组患者性别、年龄、肿瘤大小、T分期、分化程度、白蛋白比较差异无统计学意义(P>0.05);TNM分期、BMI、ASA分级比较差异有统计学意义(P<0.05)。两组患者术中和术后情况相比,VFA-H组术中出血量更多,差异有统计学意义(P<0.05);手术时间、术后首次通气时间、术后首次排便时间、术后住院时间比较差异无统计学意义(P>0.05)。单因素分析结果显示,手术时间>180 min和VFA≥100 cm^(2)是右半结肠癌术后早期并发症发生的危险因素(P<0.05);多因素分析结果显示,VFA≥100 cm^(2)是右半结肠癌术后早期并发症发生的独立危险因素(P<0.05)。结论:VFA≥100 cm^(2)是右半结肠癌术后早期并发症发生的独立危险因素。
Objective:To explore the effect of visceral obesity on the early complications after radical resection of right colon cancer.Methods:The clinicopathologic data of patients receiving radical operation for right colon cancer in the anorectal department of Gansu Provincial People's Hospital from October 2020 to October 2022 were analyzed retrospectively.The visceral fat area (VFA) was estimated based on abdominal CT data collected at one month before surgery.The patients were divided into the VFA-H group (VFA≥100 cm^(2)) and VFA-L group (VFA<100 cm^(2)).The clinicopathological features and early postoperative complications were compared between the two groups.Univariate and multivariate Logistic regression models were used to analyze the risk factors affecting the early postoperative complications of right colon cancer. Results: A total of 112 patients with right colon cancer were included in the study,including 49 patients in VFA-H group and 63 patients in VFA-L group.There were no statistically significant differences in gender,age, tumor size,T stage,degree of differentiation and albumin between the two groups ( P >0.05),while there were statistically significant differences in TNM stage,BMI and ASA grade between the two groups ( P <0.05).Through comparison of the intraoperative and postoperative conditions between the two groups,the intraoperative blood loss in VFA-H group was higher,and the difference was statistically significant ( P <0.05).There were no significant differences in operation time,first postoperative exhaust time,first postoperative defecation time and postoperative hospital stay time ( P >0.05).Univariate analysis showed that operation time>180 min and VFA≥100 cm^(2) were risk factors for early postoperative complications of right colon cancer ( P <0.05).Multivariate analysis showed that VFA≥100 cm^(2) was an independent risk factor for early postoperative complications of right colon cancer ( P <0.05). Conclusion: VFA≥100 cm^(2) is an independent risk factor for early postoperative complications of right colon cancer.