文献类型：期刊文献

中文题名：《四部医典》的跌打损伤外用方剂用药规律及药性探析

英文题名：Study on the Rules and Properties of External Prescriptions for Traumatic Injuries Based on the Classical Book of Tibetan Medicine Rgyud bzhi

作者：娘去先[1];仁增加[1];贡保东知[2];阿达[2];加羊加措[2];闹华才让[1];李先加[1,3]

第一作者：娘去先

机构：[1]青海大学藏医学院,西宁810016;[2]甘肃中医药大学藏医学院,合作747000;[3]藏药新药开发国家重点实验室,西宁810016

第一机构：青海大学藏医学院,西宁810016

年份：2021

卷号：23

期号：5

起止页码：1698

中文期刊名：世界科学技术-中医药现代化

外文期刊名：Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

收录：CSTPCD;;北大核心:【北大核心2020】；CSCD:【CSCD_E2021_2022】；

基金：藏药新药开发国家重点实验室建设项目(2015DQ870717)负责人:多杰;青海省科技厅青海省重大科技专项(2020-SF-A3-2):重点藏药品种有效性研究与安全性评价,负责人:多杰。

语种：中文

中文关键词：《四部医典》;外用方剂;用药规律;药性;跌打损伤

外文关键词：Rgyul bzhi;Prescription;Rules of prescription;Properties of medicine;Traumatic injuries

摘要：目的总结藏医治疗跌打损伤外用方剂用药规律及药性研究。方法收集《四部医典》中主治跌打损伤的外用方剂,构建藏医治疗跌打损伤外用方剂复杂网络数据集,计算网络的拓扑性质参数,分析跌打损伤外用方剂的核心药物、方药配伍规律及药性特点。结果共筛选出符合条件的外用方剂223首,涉及药物286种,药物节点度靠前的药物有甜醅、酸奶、熊胆、鱼胆、面粉、秦艽等。常用组合药物中甜醅-面粉、甜醅-酸奶、冰片-熊胆等是藏医治疗跌打损伤的常用组合药物。药物六味分析发现,甘味与苦味占主要味道;同样三化味中甘化味与苦化味居多;药物十七效分析发现,软效、重效、钝效等排名靠前。结论运用复杂网络方法可以发现藏医跌打损伤外用方剂的组方配伍规律,为总结和分析藏医外用药物提供更准确、更多维度的依据,进而或可有助于藏药新药开发提供思路。
Objective To summarize the regularity and properties of external prescriptions of Tibetan medicine for treatment of bruises. Methods The topical prescriptions for traumatic injuries in the"Rgyud bzhi"were collected to construct a complex network data set of the external prescriptions for traumatic injuries of Tibetan medicine, and to calculate the topological parameters of the network, and analyze the key medicines of the external prescriptions for traumatic injuries and the characteristics and rules of compound medications. Results A total of 223 qualified external prescriptions were screened and it involving 286 kinds of medicines. The medicines with the highest drug nodes were sweet glutinous rice, yogurt, bear bile, fish bile, flour, gentian, and sweet mash-flour, sweet mash-yogurt, borneol-bear bile were the most common drugs of using in compound medicines in Tibetan medicine to treat bruises. The six-flavor analysis of drugs found that sweetness and bitterness accounted for the main flavors;sweetness and bitterness are the main flavors from the"Three converted flavors";the seventeen-effect analysis of drugs have found that the soft effect,heavy effect, and dry effect were the main effect. Conclusion The method of using complex network is able to discover the prescription compatibility of external prescriptions for traumatic injury in Tibetan medicine, and it is helpful of providing more accurate and more dimensional basis for summarizing and analyzing the externally used Tibetan medicines, which may help provide ideas for the development of new Tibetan medicines.