文献类型：期刊文献

中文题名：熵权法优选湖北海棠叶中总黄酮提取工艺

英文题名：Optimization of Extraction Technology for Total Flavonoid from Malus hupehensis by Entropy Weighting Method

作者：李四海[1];高建德[1];陈建国[1];柳春[1]

第一作者：李四海

机构：[1]甘肃中医学院,兰州730000

第一机构：甘肃中医药大学

年份：2012

卷号：18

期号：23

起止页码：56

中文期刊名：中国实验方剂学杂志

外文期刊名：Chinese Journal of Experimental Traditional Medical Formulae

收录：CSTPCD;;北大核心:【北大核心2011】；

语种：中文

中文关键词：湖北海棠叶;熵权;综合评价;总黄酮;Matlab

外文关键词：Malus hupehensis ; entropy-weighting ; comprehensive evaluation ; total flavonoid ; Matlab

摘要：目的:采用熵权法优选湖北海棠叶中总黄酮的提取工艺。方法:以浸膏得率、总黄酮及根皮苷含量为综合评价指标,选取乙醇体积分数、溶剂用量及提取时间为影响因素,应用熵权法确定各因素的客观权重,通过Matlab编程实现提取工艺的正交试验优选。结果:最佳提取工艺为10倍量70%乙醇回流提取3次,每次1 h。结论:熵权法可用于中药提取工艺优选,使用Matlab编程可减少正交试验计算量。
Objective： To optimize extraction technology of total flavonoid from Malus hupehensis by entropy-weighting method. Method： With yield of extract, the content of total flavonoid and phloridzin as comprehensive evaluation indexes, the concentration and dosage of solvent, extraction time were selected as factors, weight of which were determined by entropy-weighting method, extraction technology was optimized by orthogonal test which was realized by Matlab. Result： Optimum extraction technology was： reflux extracted 3 times with 10 folds the amount of 70% ethanol, 1 h each time. Conclusion： Entropy-weighting method eould be used in optimizing of extraction technology for traditional Chinese medicine, calculation amount of orthogonal test could be reduced by Matlab programming.