文献类型：期刊文献

中文题名：茵陈蒿汤化裁方降脂作用的实验研究

英文题名：Experimental Study on Hyperlipemia-reducing Action of Yinchenhao Decoction Improved Presuiption(Herba Artemisiae Scopariae, Herba Lysimachiae, etc. )

作者：李茂言[1];何利城[1];刘雄[1];吴志成[1]

第一作者：李茂言

机构：[1]甘肃中医学院

第一机构：甘肃中医药大学

年份：1998

卷号：20

期号：1

起止页码：29

中文期刊名：中成药

外文期刊名：CHINESE TRADITIONAL PATENT MEDICINE

收录：CSTPCD;;CSCD:【CSCD2011_2012】；

语种：中文

中文关键词：茵陈蒿汤;化裁方;高脂血症;中医药疗法;实验

外文关键词：Yinchenhao Decoction Improved Prescription,hyperlipermia symptommodel,cholesteral,glyceryl trifatty acid ester,malon aldehyde

摘要：用Wistar大鼠建立高脂血症动物模型观察了茵陈蒿汤化裁方（IHACD）对大鼠肝脂、血脂和血清丙二醛（MDA）含量的影响。结果表明低剂量组（7．5g／kg·d）和高剂量组（15．0g／kg·d）均能明显降低肝组织胆固醇（TC）的含量，对肝组织甘油三脂（TG）影响不大，类似安妥明的作用．低剂量组能明显提高血清高密度脂蛋白胆固醇与总胆固醇的比值（HDL－C/TC），降低血清TC和TG的含量，后者优于安妥明的作用。两种剂量均能明显降低血清MDA的含量。
The effects of Yinchenhao Decoction Improved Prescription on contents of liver -fat,blood-fat and serum malon aldehyde of rats have been investigated on an animal model ofhyperlipermia symptom of Wistar rat. As a result, both low dose group (7. 5g/kg/d) andhigh dose group (15. 0g/kg/d) could obviously decrease cholesterol content of liver tissues(TC) and have no great effect on glyceryl trifatty acid ester of liver tissues (TG) like atromid-S action. But the low dose group could greatly raise the specific value of serum high density lipoprotein cholesterol to total cholesterol and was superior to atromid-S in decreasing ofTC and TG contents, Both dose groups could decrease serum malon aldehyde content.