文献类型：期刊文献

英文题名：The Genus Patrinia: A Review of Traditional Uses, Phytochemical and Pharmacological Studies

作者：He, Xirui[1,2];Luan, Fei[3,4];Zhao, Zefeng[2];Ning, Ning[1];Li, Maoxing[3,5];Jin, Ling[4];Chang, Yu[1];Zhang, Qiang[2];Wu, Ni[2];Huang, Linhong[1]

第一作者：He, Xirui

通信作者：Li, MX[1];Huang, LH[2]

机构：[1]Xi An Jiao Tong Univ, Honghui Hosp, Coll Med, 3 Nanguo Rd, Xian 710054, Peoples R China;[2]Northwest Univ, Minist Educ, Key Lab Resource Biol & Biotechnol Western China, Xian 710069, Peoples R China;[3]Gansu Univ Chinese Med, Dept Pharm, Lanzhou 730000, Peoples R China;[4]Xian Weiyang Dist Hosp Tradit Chinese Med, Dept Pharm, Xian 710016, Peoples R China;[5]Lanzhou Gen Hosp PLA, Dept Pharm, Key Lab Prevent & Treatment Injury Plateau PLA, Lanzhou 730050, Peoples R China

第一机构：Xi An Jiao Tong Univ, Honghui Hosp, Coll Med, 3 Nanguo Rd, Xian 710054, Peoples R China

通信机构：[1]corresponding author), Xi An Jiao Tong Univ, Honghui Hosp, Coll Med, 3 Nanguo Rd, Xian 710054, Peoples R China;[2]corresponding author), Lanzhou Gen Hosp PLA, Dept Pharm, 333 Binhe Rd, Lanzhou 730050, Peoples R China.

年份：2017

卷号：45

期号：4

起止页码：637

外文期刊名：AMERICAN JOURNAL OF CHINESE MEDICINE

收录：;Scopus(收录号：2-s2.0-85020405058);WOS:【SCI-EXPANDED(收录号:WOS:000403414600001)】；

基金：This work was supported by 2014 CAS "Light of West China". The authors also would like to express their gratitude to Dr. Allan Grey at Lanzhou University for correcting the English in this paper.

语种：英文

外文关键词：Genus Patrinia; Traditional Uses; Phytochemistry; Pharmacology; Antitumor; Anti-inflammatory; Review

摘要：The aim of the present review is to comprehensively outline the botanical description, traditional uses, phytochemistry, pharmacology and toxicology of Patrinia, and to discuss possible trends for the further study of medicinal plants from the genus Patrinia. The genus Patrinia plays an important role in Asian medicine for the treatment of erysipelas, conjunctival congestion with swelling and pain, peri-appendicular abscesses, lung carbuncle, dysentery, leucorrhea, and postpartum disease. More than 210 chemical constituents have been isolated and identified from Patrinia plants, especially P. scabiosaefolia Fisch., P. scabra Bunge, P. villosa Juss., P. heterophylla Bunge and P. rupestris (Pall.) Juss: Of these compounds, triterpenoids and saponins, iridoids, flavonoids, and lignans are the major or active constituents. Both in vitro and in vivo studies have indicated that some monomer compounds and crude extracts from the genus Patrinia possess wide pharmacological activities, including antitumor, anti-inflammatory, antibacterial, and antiviral effects. In addition, they have been shown to have valuable and positive effects on the immune and nervous system in experimental animals. There are also some reports on the clinical uses and toxicity of these species. However, few reports have been published concerning the material identification or quality control of Patrinia species, and the clinical uses and toxic effects of these plants are relatively sparse. More attention must be given to these issues.