详细信息
Th17/Treg细胞与高血压相关性的研究现状
Research status of the relationship between Th17/Treg cells and hypertension
文献类型:期刊文献
中文题名:Th17/Treg细胞与高血压相关性的研究现状
英文题名:Research status of the relationship between Th17/Treg cells and hypertension
作者:龚玉栓[1];王倩[1];魏惠平[2]
第一作者:龚玉栓
机构:[1]甘肃中医药大学中西医结合学院,甘肃兰州730000;[2]甘肃中医药大学附属医院心血管科,甘肃兰州730020
第一机构:甘肃中医药大学中西医结合学院
年份:2024
卷号:40
期号:20
起止页码:3056
中文期刊名:中国临床药理学杂志
外文期刊名:The Chinese Journal of Clinical Pharmacology
收录:CSTPCD;;北大核心:【北大核心2023】;CSCD:【CSCD2023_2024】;
基金:甘肃省自然科学基金资助项目(21JR7RA581);甘肃省中医药管理局课题资助项目(GZKZ-2020-9);甘肃中医药大学附属医院院内创新基金资助项目(KC2018-18)。
语种:中文
中文关键词:辅助性T细胞17;调节性T细胞;高血压
外文关键词:T helper cell 17;regulatory T cell;high blood pressure
摘要:高血压作为一种常见的慢性疾病,其发病率在全球范围内逐年上升,且病理机制复杂,涉及遗传、环境、生活方式等多种因素。近年来,免疫-炎症机制在高血压发病中的作用逐渐受到关注。特别是辅助性T细胞17(Th17)和调节性T细胞(Treg),作为免疫系统中的重要组成部分,其平衡状态对高血压的影响成为研究热点。本文将对Th17/Treg与高血压相关性的研究进展进行综述,为高血压的免疫治疗和预防提供新的思路和方法。
Hypertension is a common chronic disease,and its incidence is increasing year by year worldwide.Its pathological mechanism is complex,involving genetics,environment,lifestyle and other factors.In recent years,the role of immune-inflammatory mechanism in the pathogenesis of hypertension has gradually attracted attention.Especially T helper cell 17(Th17)and regulatory T cells(Treg),as important components of the immune system,the effect of their balance on hypertension has become a research hotspot.This article reviews the research progress of the correlation between Th17/Treg and hypertension,in order to provide new ideas and methods for the immunotherapy and prevention of hypertension.
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