详细信息
半夏化学成分和药理作用的研究进展及其质量标志物预测分析 被引量:4
Research progress on chemical constituents and pharmacological effects of Pinelliae Rhizoma and predictive analysis of quality marker
文献类型:期刊文献
中文题名:半夏化学成分和药理作用的研究进展及其质量标志物预测分析
英文题名:Research progress on chemical constituents and pharmacological effects of Pinelliae Rhizoma and predictive analysis of quality marker
作者:张国玉[1];熊继东[1];魏家艳[1];仲楠[1];强宇靖[1];李芸[1]
第一作者:张国玉
机构:[1]甘肃中医药大学药学院、甘肃陇药产业创新研究院、西北中藏药省部共建协同创新中心,甘肃兰州730000
第一机构:甘肃中医药大学药学院(西北中藏药协同创新中心办公室)
年份:2024
卷号:39
期号:1
起止页码:110
中文期刊名:华西药学杂志
外文期刊名:West China Journal of Pharmaceutical Sciences
收录:CSTPCD;;北大核心:【北大核心2023】;CSCD:【CSCD_E2023_2024】;
基金:甘肃省科技计划项目(22CX8NK244);中药材及饮片质量控制重点实验室项目(2021GSMPA-KL08)。
语种:中文
中文关键词:半夏;化学成分;药理作用;质量标志物;左旋麻黄碱;葫芦巴碱;苷类;β-谷甾醇;有机酸
外文关键词:Pinelliae Rhizoma;Chemical composition;Pharmacological effect;Quality marker;Levoephedrine;Trigonelline;Glycosides;β-sitosterol;Organic acid
摘要:利用CNKI、PubMed、万方等数据库,对半夏Pinelliae Rhizoma的化学成分及药理作用进行整理,发现左旋麻黄碱、葫芦巴碱、腺苷、胸苷、尿苷、鸟苷、β-谷甾醇、亚油酸、棕榈酸、琥珀酸、苹果酸、天冬氨酸等成分可作为其主要质量标志物,可为半夏的质量控制研究提供基础。
In this paper,CNKI,PubMed,Wanfang and other databases were used to sort out the chemical constituents and pharmacological effects of Pinelliae Rhizoma,and on this basis,the quality markers of Pinelliae Rhizoma were predicted and analyzed.The results showed that levoephedrine,trigonelline,adenosine,thymidine,uridine,guanoside,β-sitosterol,linoleic acid,palmitic acid,succinic acid,malic acid and aspartic acid could be used as the main quality markers of Pinelliae Rhizoma,in order to provide the basis for quality control research.
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