文献类型：期刊文献

中文题名：基于OPLS结合熵权TOPSIS法对不同产地锁阳的鉴别与综合质量评价

英文题名：Identification and comprehensive quality evaluation of Cynomorium songaricum in different producing areas based on OPLS combined with entropy weight TOPSIS method

作者：马天翔[1];顾志荣[2];许爱霞[2];祁梅[2];吕鑫[1];孙岚萍[1];马转霞[1];葛斌[2]

第一作者：马天翔

机构：[1]甘肃中医药大学药学院,甘肃兰州730000;[2]甘肃省人民医院药剂科,甘肃兰州730000

第一机构：甘肃中医药大学药学院（西北中藏药协同创新中心办公室）

年份：2020

卷号：51

期号：12

起止页码：3284

中文期刊名：中草药

外文期刊名：Chinese Traditional and Herbal Drugs

收录：CSTPCD;;Scopus;北大核心:【北大核心2017】；CSCD:【CSCD2019_2020】；

基金：甘肃省中药药理与毒理学重点实验室基金项目(ZDSYS-KJ-2018-010);甘肃省中药质量与标准研究重点实验室基金项目(ZYZL18-004)。

语种：中文

中文关键词：锁阳;正交偏最小二乘判别分析法;熵权TOPSIS法;产地鉴别;综合评价;没食子酸;原儿茶酸;儿茶素

外文关键词：Cynomorium songaricum Rupr.;orthogonal partial least squares discriminant analysis;entropy TOPSIS method;producing areas identification;comprehensive evaluation;gallic acid;protocatechuic acid;catechin

摘要：目的对不同产地的锁阳Cynomorium songaricum药材进行产地鉴别与综合评价,为锁阳药材质量评价与产地适宜性的确定提供参考。方法收集全国5省(区)的40批样品,测定锁阳中没食子酸、原儿茶酸、儿茶素、总多糖、总黄酮、Na、K、Ca、Mg、Fe、Zn、Mn、Co、Sr、Ni、Ag、Ba、Ti、Cu、Pb、Cr、Cd、As、Hg含量,运用正交偏最小二乘判别分析法(OPLS-DA)和熵权TOPSIS法对反映药材质量的数据进行分析。结果锁阳中儿茶素、原儿茶酸、总黄酮、Mn、Zn、Co、Pb、Cr、Ca、Ti、Mg和Cu的含量差异可用于不同产地的区分;5个省(区)中内蒙古地区的锁阳药材质量最优,其次为甘肃、宁夏、新疆、青海。结论OPLS-DA结合熵权TOPSIS分析法结果合理、客观、有效,可应用于锁阳药材质量的多指标综合评价。
Objective To identify and comprehensively evaluate Cynomorium songaricum from different producing areas in order to provide reference for the quality evaluation of C.songaricum and the determination of the suitability of the origin.Methods A total of 40 samples from five provinces(regions)were collected to measure the content of gallic acid,protocatechuic acid,catechins,total polysaccharides,total flavonoids,Na,K,Ca,Mg,Fe,Zn,Mn,Co,Sr,Ni,Ag,Ba,Ti,Cu,Pb,Cr,Cd,As,and Hg.The data reflecting the quality of C.songaricum were analyzed by orthogonal partial least squares discriminant analysis(OPLS-DA)and entropy weight TOPSIS analysis.Results The contents of Mn,Zn,Co,catechin,Pb,Cr,Ca,Ti,total flavonoids,protocatechuic acid,Mg and Cu in C.songaricum are important for distinguishing different producing areas.The quality of C.songaricum in Inner Mongolia was the best in all provinces(regions),followed by Gansu,Ningxia,Xinjiang,and Qinghai Provinces.Conclusion The results of OPLS-DA combined with entropy weight TOPSIS analysis are reasonable,objective and effective,and can be applied to the comprehensive evaluation of multiple indicators of C.songaricum.