文献类型：期刊文献

英文题名：Association of relative fat mass with female infertility: a cross-sectional study based on NHANES 2017-2020

作者：Tang, Qian[1,2];Zhang, Qiang[2];Xia, Rui[2];Li, Xitong[1];Du, Jing[1,2];Cheng, Yaoping[1];Wang, Ling[1]

第一作者：Tang, Qian

通信作者：Wang, L[1]

机构：[1]PLA, Reprod Ctr, Hosp Joint Logist Support Force 940, Lanzhou 730050, Peoples R China;[2]Gansu Univ Chinese Med, Lanzhou, Peoples R China

第一机构：PLA, Reprod Ctr, Hosp Joint Logist Support Force 940, Lanzhou 730050, Peoples R China

通信机构：[1]corresponding author), PLA, Reprod Ctr, Hosp Joint Logist Support Force 940, Lanzhou 730050, Peoples R China.

年份：2025

卷号：15

期号：1

外文期刊名：SCIENTIFIC REPORTS

收录：;Scopus(收录号：2-s2.0-105009549078);WOS:【SCI-EXPANDED(收录号:WOS:001523016300009)】；

基金：We wish to thank all the patients and the staff members of the medical staff for their cooperation.

语种：英文

外文关键词：Relative fat mass; Infertility; NHANES; Body fat; Reproductive health

摘要：Relative Fat Mass (RFM) is an emerging body fat measurement index that more accurately reflects the distribution of visceral fat. This study aimed to investigate the association between RFM and female infertility. We utilized data from the National Health and Nutrition Examination Survey (NHANES) spanning from 2017 to 2020, enrolling 1487 female participants aged 20-44. The relationship between RFM and infertility was analyzed using multivariate Logistic regression, and the dose-response relationship was assessed with Restricted Cubic Splines (RCS). The study found a significant association between RFM and infertility. After adjusting for confounders such as age, ethnicity, and BMI, each unit increase in RFM was associated with a 6% increase in the risk of infertility (OR = 1.06, 95%CI = 1.01-1.12, P = 0.019), with stable results across different subgroups. RFM is significantly associated with female infertility and may serve as a useful tool in infertility screening. Future studies should further validate its potential for clinical application.