文献类型：期刊文献

中文题名：单味中药治疗肾虚型骨质疏松症机制研究状况

英文题名：Current situation on mechanism of single traditional Chinese medicine for treatment of kidney deficiency type osteoporosis

作者：彭斯伟[1];宋敏[1,2];范凯[1];董万涛[2];宋志靖[1,3];王凯[1]

第一作者：彭斯伟

机构：[1]甘肃中医药大学中医临床学院,甘肃兰州730000;[2]甘肃中医药大学附属医院运动关节科,甘肃兰州730000;[3]甘肃中医药大学附属医院康复骨科,甘肃兰州730000

第一机构：甘肃中医药大学中医临床学院

年份：2022

卷号：38

期号：1

起止页码：76

中文期刊名：中国临床药理学杂志

外文期刊名：The Chinese Journal of Clinical Pharmacology

收录：CSTPCD;;北大核心:【北大核心2020】；CSCD:【CSCD2021_2022】；

基金：国家自然科学基金地区科学基金资助项目(81960877,81960878);甘肃中医药大学研究生创新基金资助项目(2021CX05)。

语种：中文

中文关键词：骨质疏松症;单味中药;肾虚;信号通路

外文关键词：osteoporosis;single Chinese medicine;kidney empty;signaling pathway

摘要：激素替代疗法和阿仑膦酸钠常作为治疗骨质疏松症的主要治疗策略,但其不良反应严重限制了其在临床上的广泛应用,因此,迫切需要开发替代或补充治疗药物用于抗骨质疏松。中药被认为是治疗骨质疏松症安全有效的药物。诸多研究阐明了单味中药的抗骨质疏松作用和机制,是一种有效的治疗药物。因此,本研究综述了部分中药抗骨质疏松症的机制,不仅有助于我们进一步认识中药作用,而且为中药治疗骨质疏松症的临床应用提供了新的证据。
Hormone replacement therapy and alendronate sodium are often used as the main treatment strategies for osteoporosis, but their adverse reactions seriously limit their wide clinical application. Therefore, it is urgent to develop alternative or complementary drugs for anti-osteoporosis. Chinese medicine is considered safe and effective in the treatment of osteoporosis. Many studies have clarified the anti-osteoporosis effect and mechanism of single Chinese medicine, which is an effective treatment drug. Therefore, this study reviewed the anti-osteoporosis mechanism of some Chinese medicines, which not only helps us to further understand the effects of Chinese medicines, but also provides new evidence for the clinical application of Chinese medicines in the treatment of osteoporosis.