文献类型：期刊文献

英文题名：Association between CYP2A13 polymorphisms and lung cancer A protocol for systematic review and meta-analysis

作者：Ma, Long[1,2];Jin, Gang[2];Yang, Yi[1,2];Pang, Yao[2];Wang, Wenhao[2];Zhang, Hongyi[2];Liu, Jiawei[2];Wu, Peng[1,2];Wang, Zequan[2];Wang, Kui[1,2];Chang, Ruitong[2];Li, Jialong[2];Zhu, Zijiang[2]

第一作者：马利;Ma, Long

通信作者：Zhu, ZJ[1]

机构：[1]Gansu Univ Tradit Chinese Med, Dept Clin Med, Lanzhou, Peoples R China;[2]Gansu Prov Hosp, Dept Thorac Surg, Lanzhou 730000, Peoples R China

第一机构：甘肃中医药大学临床医学院

通信机构：[1]corresponding author), Gansu Prov Hosp, Dept Thorac Surg, Lanzhou 730000, Peoples R China.

年份：2020

卷号：99

期号：50

起止页码：E23289

外文期刊名：MEDICINE

收录：;Scopus(收录号：2-s2.0-85098606021);WOS:【SCI-EXPANDED(收录号:WOS:000612838800035)】；

基金：This work was supported by grants from the National Natural Science Foundation of China (Nos. 31760259).

语种：英文

外文关键词：lung cancer; meta-analysis; polymorphism

摘要：Background: Recently, lung cancer has become the most common cause of cancer-related death, several studies indicate that the cytochrome P450 2A13 (CYP2A13) polymorphisms may be correlated with lung cancer susceptibility, but the results have been inconsistent and inconclusive. Therefore, the aim of this meta-analysis is to provide a precise conclusion on the potential association between CYP2A13 polymorphisms and the risk of lung cancer based on case-control studies. Methods: The PubMed, Embase, Cochrane Library, Web of Science, and China National Knowledge Infrastructure (CNKI) databases will be searched for case-control studies published up to September 2020. Odds ratio (OR) and 95% confidence interval (95% CI) were used to determine the effects of the CYP2A13 polymorphism on lung cancer risk, respectively. Results: The results of this meta-analysis will be submitted to a peer-reviewed journal for publication. Conclusion: This meta-analysis will summarize the association between CYP2A13 polymorphisms and the risk of lung cancer. INPLASY registration number: INPLASY202090102