文献类型：期刊文献

英文题名：Association between segmental noninvasive longitudinal strain and quantitative microvascular perfusion in ST-segment elevation myocardial infarction: implications for clinical outcomes

作者：Zhang, Rui[1];Liang, Shuxin[2];Zhao, Fan[1];Du, Bang[1];Wang, Ruo-Nan[1];Shi, Wen-Jia[1];Chu, Ai-Ai[1,3]

第一作者：张蕊

通信作者：Chu, AA[1];Chu, AA[2]

机构：[1]Gansu Univ Chinese Med, Gansu Prov Hosp, Clin Med Sch 1, Dept Echocardiog, Lanzhou, Peoples R China;[2]Shenzhen Ruipuxun Acad Stem Cell & Regenerat Med, Shenzhen, Peoples R China;[3]Gansu Prov Hosp, Dept Echocardiog, 204 West Donggang Rd, Lanzhou, Gansu, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Gansu Prov Hosp, Clin Med Sch 1, Dept Echocardiog, Lanzhou, Peoples R China;[2]corresponding author), Gansu Prov Hosp, Dept Echocardiog, 204 West Donggang Rd, Lanzhou, Gansu, Peoples R China.|[10735]甘肃中医药大学;

年份：2025

卷号：25

期号：1

外文期刊名：BMC CARDIOVASCULAR DISORDERS

收录：;Scopus(收录号：2-s2.0-85218492674);WOS:【SCI-EXPANDED(收录号:WOS:001425121400005)】；

基金：We would like to thank Gansu Provincial Hospital for their support and contributions to this research.

语种：英文

外文关键词：Longitudinal strain; Quantitative microvascular perfusion; Myocardial infarction

摘要：Objective This study aims to investigate the relationship between segmental longitudinal strain (LS) and quantitative microvascular perfusion (qMVP) in patients with ST-segment elevation myocardial infarction (STEMI), and to explore the prognostic value of the two indicators after STEMI. Methods The retrospective study enrolled 61 patients who underwent primary percutaneous coronary intervention (pPCI) for first STEMI. Microvascular perfusion (MVP) and qMVP were analyzed by myocardial contrast echocardiography (MCE), and segmental LS was analyzed by two-dimensional speckle tracking echocardiography (2D-STE). Myocardial wall perfusion was qualitatively assessed visually. Quantitative myocardial perfusion parameters were analyzed using an 18-segment model. The correlation between segmental LS and qMVP was assessed. The prognostic value of segmental LS and qMVP for major cardiac adverse events were evaluated. Results Among the 314 segments with abnormal wall motion, 44 showed normal microvascular perfusion (nMVP), 87 showed delayed microvascular perfusion (dMVP), and 183 exhibited microvascular obstruction (MVO). Segmental LS was correlated with segmental wall motion (WM) and qMVP. At 12-month follow-up, 19 patients experienced cardiac events. NT-proBNP, regional LS (rLS), and regional qMVP (r-qMVP) were associated with cardiac events. The area under curve (AUC) of combination of rLS and r-qMVP was bigger than single indicator for identifying prognostic value (P < 0.001). Conclusion Segmental LS indices are correlated with qMVP within the infarct zone following reperfused STEMI. Both rLS and r-qMVP are sensitive to myocardial damage and provide prognostic value for clinical events after STEMI. And the combination of rLS and r-qMVP shows improved predictive ability compared to a single indicator.