文献类型：期刊文献

英文题名：Prophylactic effects of nutrition, dietary strategies, exercise, lifestyle and environment on nonalcoholic fatty liver disease

作者：Hao, Xiangyong[1];Song, Hao[2];Su, Xin[1,2];Li, Jian[1,2];Ye, Youbao[1,2];Wang, Cailiu[1,2];Xu, Xiao[1,2];Pang, Guanglong[1,2];Liu, Wenxiu[1,2];Li, Zihan[2];Luo, Tian[3]

第一作者：Hao, Xiangyong

通信作者：Hao, XY[1];Luo, T[2]

机构：[1]Gansu Prov Hosp, Dept Gen Surg, 204 Donggang West Rd, Lanzhou 730000, Peoples R China;[2]Gansu Univ Chinese Med, Gansu Prov Hosp, Dept Clin Med, Clin Med Coll 1, Lanzhou, Peoples R China;[3]Gansu Prov Hosp, Inst Clin Res & Translat Med, Lanzhou 730000, Peoples R China

第一机构：Gansu Prov Hosp, Dept Gen Surg, 204 Donggang West Rd, Lanzhou 730000, Peoples R China

通信机构：[1]corresponding author), Gansu Prov Hosp, Dept Gen Surg, 204 Donggang West Rd, Lanzhou 730000, Peoples R China;[2]corresponding author), Gansu Prov Hosp, Inst Clin Res & Translat Med, Lanzhou 730000, Peoples R China.

年份：2025

卷号：57

期号：1

外文期刊名：ANNALS OF MEDICINE

收录：;Scopus(收录号：2-s2.0-85218044577);WOS:【SCI-EXPANDED(收录号:WOS:001419926300001)】；

基金：This work was supported by Natural Science Foundation of Gansu Province (Grant No.: 23JRRA1313), Natural Science Foundation for Young Scientists and the Science & Technology Planning Project of Gansu Province (Grant No.: 18JR3RA058), Gansu Province Youth Innovative Talents Project (Grant No.: 2021LQGR15), Health Industry Scientific Research Program of Gansu Province (Grant No.: GSWSKY2020-06), and Research Projects of Gansu Provincial Hospital (Grant No.: 19SYPYB-7, 18GSSY3-1).

语种：英文

外文关键词：Nonalcoholic fatty liver disease; nutrition; dietary strategies; exercise; lifestyle; environment; prevention

摘要：BackgroundNonalcoholic fatty liver disease (NAFLD) is a chronic liver disease and its prevalence has risen sharply. However, whether nutrition, dietary strategies, exercise, lifestyle and environment have preventive value for NAFLD remains unclear.MethodsThrough searching 4 databases (PubMed, Web of Science, Embase and the Cochrane Library) from inception to January 2025, we selected studies about nutrition, dietary strategies, exercise, lifestyle and environment in the prevention of NAFLD and conducted a narrative review on this topic.ResultsReasonable nutrient intake encompassing macronutrients and micronutrients have an independent protective relationship with NAFLD. Besides, proper dietary strategies including mediterranean diet, intermittent fasting diet, ketogenic diet, and dietary approaches to stop hypertension diet have their inhibitory effects on the developmental process of NAFLD. Moreover, right exercises including walking, jogging, bicycling, and swimming are recommended for the prevention of NAFLD because they could effectively reduce weight, which is an important risk factor for NAFLD, and improve liver function. In addition, embracing a healthy lifestyle including reducing sedentary behavior, not smoking, sleeping well and brushing teeth regularly is integral since it not only could reduce the risk of NAFLD but also significantly contribute to overall prevention and control. Finally, the environment, including the social and natural environments, plays a potential role in NAFLD prevention.ConclusionNutrition, dietary strategies, exercise, lifestyle and environment play an important role in the prevention of NAFLD. Moreover, this review offers comprehensive prevention recommendations for people at high risk of NAFLD.