文献类型：期刊文献

中文题名：干眼危险因素的Meta分析

英文题名：Meta-analysis of Risk Factors for Dry Eye

作者：郑思雨[1,2];燕振国[2];杨刚[2]

第一作者：郑思雨

机构：[1]甘肃中医药大学第一临床医学院/甘肃省人民医院眼科,甘肃兰州730000;[2]兰州华厦眼科医院/甘肃中医药大学附属眼科中心,甘肃兰州730000

第一机构：甘肃中医药大学临床医学院

年份：2023

卷号：36

期号：7

起止页码：117

中文期刊名：医学信息

外文期刊名：Journal of Medical Information

语种：中文

中文关键词：干眼;危险因素;角膜疾病

外文关键词：Dry eye;Risk factors;Corneal disease

摘要：目的通过Meta分析的方法评估干眼的危险因素。方法计算机检索PubMed、EMbase、Web of Science、Cochrane Library、CBM、CNKI、万方和VIP数据库有关干眼危险因素的研究,运用纽卡斯尔-渥太华量表(NOS)对纳入的文献进行质量评价。采用STATA 16.0和RevMan5.3软件进行Meta分析。结果确定纳入16篇文献。Meta分析结果显示:女性(OR=1.98,95%CI:1.40~2.80)、糖尿病(OR=4.03,95%CI:2.84~5.73)、角膜疾病(OR=5.05,95%CI:3.00~8.48)、使用视觉显示终端(VDT)(OR=2.45,95%CI:2.02~2.96)、长时间用眼(OR=1.55,95%CI:1.15~2.09)、频繁使用滴眼液(OR=3.35,95%CI:2.43~4.60)、角膜接触镜或隐形眼镜(OR=4.57,95%CI:2.76~7.55)、长期处于不良环境(OR=2.16,95%CI:1.54~3.02)是该病的危险因素。结论女性、糖尿病、角膜疾病、VDT、长时间用眼、频繁使用滴眼液、角膜接触镜或隐形眼镜、长期处于不良环境是干眼疾病的危险因素。
Objective To evaluate the risk factors of dry eye by Meta-analysis.Methods PubMed,EMbase,Web of Science,Cochrane Library,CBM,CNKI,Wanfang and VIP databases were searched for studies on risk factors for dry eye.The Newcastle-Ottawa Scale(NOS)was used to evaluate the quality of the included literature.Meta-analysis was performed using STATA 16.0 and RevMan5.3 software.Results A total of 16 articles were included.The results of meta-analysis showed that female(OR=1.98,95%CI:1.40-2.80),diabetes(OR=4.03,95%CI:2.84-5.73),corneal disease(OR=5.05,95%CI:3.00-8.48),use of visual display terminal(VDT)(OR=2.45,95%CI:2.02-2.96),long-term use of eyes(OR=1.55,95%CI:1.15-2.09),frequent use of eye drops(OR=3.35,95%CI:2.43-4.60),contact lens or contact lens(OR=4.57,95%CI:2.76-7.55),long-term adverse environment(OR=2.16,95%CI:1.54-3.02).Conclusion Female,diabetes,corneal disease,VDT,long-term use of eyes,frequent use of eye drops,contact lenses or contact lenses,and long-term adverse environment are risk factors for dry eye disease.