文献类型：期刊文献

英文题名：Association of adverse childhood experiences with diabetes: A systematic review and meta-analysis

作者：Zhang, Yiyin[1];Yin, Yuhuan[1];Zhang, Xiaoli[1];Ye, Jianying[1];Zhang, Juxia[2]

第一作者：张彦彦;张芸燕;张延英

通信作者：Zhang, JX[1]

机构：[1]Gansu Univ Chinese Med, Sch Nursing, Lanzhou 730000, Gansu, Peoples R China;[2]Gansu Prov Hosp, Clin Educ Dept, Lanzhou 730000, Gansu, Peoples R China

第一机构：甘肃中医药大学护理学院

通信机构：[1]corresponding author), Gansu Prov Hosp, Clin Educ Dept, Lanzhou 730000, Gansu, Peoples R China.

年份：2022

卷号：36

期号：10

外文期刊名：JOURNAL OF DIABETES AND ITS COMPLICATIONS

收录：;Scopus(收录号：2-s2.0-85137017745);WOS:【SCI-EXPANDED(收录号:WOS:000861022000002)】；

基金：Funding This research was funded by Health Industry Scientific Research Project of Gansu Province (GSWSKY-2019-50) and Natural Science Foundation of Gansu Province (Grant Nos. 21JR7RA607) .

语种：英文

外文关键词：Adverse childhood experiences; Diabetes; Meta -analysis

摘要：Background: Further clarification is needed regarding the association between adverse childhood experiences (ACEs) and the risk of diabetes. To conduct a systematic review with meta-analysis of studies assessing the as-sociation between ACEs and the risk of diabetes. Method: We conducted a systematic literature search of PubMed, Embase, and Cochrane Library for published studies describing the association between ACEs and diabetes in December 2021. We examined the overall relationship between ACEs and diabetes and performed a subgroup analysis based on the type of ACEs, number of ACEs, and gender. Results: A total of 17 studies were included. The results of Meta-analysis showed the significant estimated effect of ACEs on diabetes (OR = 1.20, 95%CI: 1.07, 1.35). The subgroup analysis found a significant association between neglect (OR = 1.61, 95%CI: 1.11, 2.33), family dysfunction (OR = 1.14, 95%CI: 1.05, 1.24) and dia-betes, respectively. Gender and the number of ACEs were factors that significantly affect the risk of diabetes. Conclusion: The results suggest that ACEs were significantly associated with an elevated risk of diabetes, espe-cially for exposure to neglect, family dysfunction, and two or more ACES. Effective ACEs screening for children and intervention among high-risk populations should be taken so as to reduce the incidence of diabetes.