文献类型：期刊文献

英文题名：Antioxidant activities of extracts and flavonoid compounds from Oxytropis falcate Bunge

作者：Jiang, H.[1];Zhan, W. Q.[2];Liu, X.[1];Jiang, S. X.[1]

第一作者：Jiang, H.

通信作者：Jiang, H[1]

机构：[1]Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China;[2]Gansu Acad Tradit Chinese Med, Lanzhou, Peoples R China

第一机构：Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China

通信机构：[1]corresponding author), Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China.

年份：2008

卷号：22

期号：18

起止页码：1650

外文期刊名：NATURAL PRODUCT RESEARCH

收录：;Scopus(收录号：2-s2.0-57849088192);WOS:【SCI-EXPANDED(收录号:WOS:000261676400012)】；

基金：This work was supported by the Research Fund of the Chinese Academy of Sciences, P. R. of China "The study on the standard of characteristic national drugs in western China''. Project number KGCX2-SW-213-08.

语种：英文

外文关键词：Oxytropis falcate; extracts; flavonoids; antioxidant activity; DPPH

摘要：The antioxidant properties of the various extracts and flavonoids prepared from Oxytropis falcate Bunge were investigated by 1,1-diphenyl-2-picryldydrazyl (DPPH) radical-scavenging assay. In the chloroform, ethyl acetate and n-butanol extracts, the ethyl acetate extract exhibited the highest antioxidant activity (IC50 = 2.05 mg mL(-1)). Furthermore, rhamnocitrin, kaempferol, rhamnetin, 2',4'-dihydroxychalcone and 2',4', beta-trihydroxy-dihydrochalcone were purified from chloroform and ethyl acetate extracts. The radical-scavenging activities of the five compounds were also measured and the results showed that kaempferol (IC50 = 0.11 mg mL(-1)), rhamnetin (IC50 = 0.14 mg mL(-1)) and rhamnocitrin (IC50 = 0.15 mg mL(-1)) exhibited considerable antioxidant activities, but the antioxidant activities of the two dihydrochalcones were very weak. Although these flavonoids are known, this is the first report of antioxidant activity in this plant.