详细信息

中药治疗缺血性脑卒中作用的研究现状     被引量:4

Research status on the role of traditional Chinese medicine in the treatment of ischemic stroke

文献类型:期刊文献

中文题名:中药治疗缺血性脑卒中作用的研究现状

英文题名:Research status on the role of traditional Chinese medicine in the treatment of ischemic stroke

作者:石露萍[1];张育贵[1];马燕[1];柳军玺[2];余琰[1]

第一作者:石露萍

机构:[1]甘肃中医药大学药学院,甘肃兰州730000;[2]中国科学院兰州化学物理研究所、西北特色植物资源化学重点实验室、甘肃省天然药物重点实验室,甘肃兰州730000

第一机构:甘肃中医药大学药学院(西北中藏药协同创新中心办公室)

年份:2023

卷号:39

期号:23

起止页码:3495

中文期刊名:中国临床药理学杂志

外文期刊名:The Chinese Journal of Clinical Pharmacology

收录:CSTPCD;;北大核心:【北大核心2020】;CSCD:【CSCD2023_2024】;

基金:甘肃省中医药研究中心开放课题基金资助项目(zyzx-2020-29);甘肃省科技厅揭榜挂帅基金资助项目(21ZD2JA004)。

语种:中文

中文关键词:中药单体;单味中药;中药复方;缺血性脑卒中;作用机制

外文关键词:traditional Chinese medicine monomer;single flavor of Chinese medicine;traditional Chinese medicine compound;ischemic stroke;mechanism of action

摘要:缺血性脑卒中是指由于脑的供血动脉狭窄或闭塞、脑供血不足导致的脑组织坏死的总称,中医称之为“中风”,具有高发病率、高致残率、高复发率、高死亡率等特点,严重威胁患者健康和生活质量,加重社会负担。中药可以通过改善氧化应激、凋亡、炎症反应、钙超载等因素来缓解脑缺血后造成的损伤。本文对缺血性脑卒中中医病因病机及中药治疗缺血性脑卒中的药理作用及作用机制的研究现状进行综述,以期为中医药诊治缺血性脑卒中和今后进一步探讨其作用机制提供参考。
Ischemic stroke refers to the general term of brain tissue necrosis caused by the stenosis or occlusion of the cerebral blood supply artery and the insufficiency of cerebral blood supply.It is called"stroke"in traditional Chinese medicine.It has the characteristics of high incidence rate,high disability rate,high recurrence rate,high mortality,etc.which seriously threatens the health and quality of life of patients and increases the social burden.This article reviews the research status on the etiology and pathogenesis of ischemic stroke in traditional Chinese medicine,as well as the pharmacological effects and mechanisms of traditional Chinese medicine in treating ischemic stroke.It aims to provide reference for the diagnosis and treatment of ischemic stroke in traditional Chinese medicine and further exploration of its mechanism of action in the future.

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