文献类型：期刊文献

英文题名：Electrochemically reduced graphene oxide-based electrochemical sensor for the sensitive determination of ferulic acid in A-sinensis and biological samples

作者：Liu, Linjie[1];Gou, Yuqiang[2];Gao, Xia[1];Zhang, Pei[1];Chen, Wenxia[1];Feng, Shilan[1];Hu, Fangdi[1];Li, Yingdong[3]

第一作者：Liu, Linjie

通信作者：Hu, FD[1]

机构：[1]Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China;[2]Lanzhou Mil Command Ctr Dis Prevent & Control, Lanzhou 730000, Peoples R China;[3]Gansu Coll Tradit Chinese Med, Lanzhou 730000, Peoples R China

第一机构：Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China

通信机构：[1]corresponding author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.

年份：2014

卷号：42

起止页码：227

外文期刊名：MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000340687400031)】；

基金：This work is kindly supported by the supports of the "Twelfth Five-Year" National Science and Technology Support Program of China (No.2011BAI05B02). This work is also supported by the Project of Science and Technology Agency of Gansu (1208RTZA211) and Lanzhou (No. 2012-2-67) and the item of scientific and technological research from Gansu province administration bureau of traditional Chinese medicine (GZK-2011-73).

语种：英文

外文关键词：Ferulic acid; Electrochemically reduced graphene oxide; Electrodeposition; Cyclic voltammetry; Differential pulse voltammetry

摘要：An electrochemically reduced graphene oxide (ERGO) modified glassy carbon electrode (GCE) was used as a new voltammetric sensor for the determination of ferulic acid (FA). The morphology and microstructure of the modified electrodes were characterized by scanning electron microscopy (SEM) and Raman spectroscopy analysis, and the electrochemical effective surface areas of the modified electrodes were also calculated by chronocoulometry method. Sensing properties of the electrochemical sensor were investigated by means of cyclic voltammetry (CV) and differential pulse voltammetry (DPV). It was found that ERGO was electrodeposited on the surface of GCE by using potentiostatic method. The proposed electrode exhibited electrocatalytic activity to the redox of FA because of excellent electrochemical properties of ERGO. The transfer electron number (n), electrode reaction rate constant (k(s)) and electron-transfer coefficient (alpha) were calculated as 1.12, 1.24 s(-1,) and 0.40, respectively. Under the optimized conditions, the oxidation peak current was proportional to FA concentration at 8.49 x 10(-8) mol L-1 to 3.89 x 10(-5) mol L-1 with detection limit of 2.06 x 10(-8) mol L-1. This fabricated sensor also displayed acceptable reproducibility, long-term stability, and high selectivity with negligible interferences from common interfering species. The voltammetric sensor was successfully applied to detect FA in A. sinensis and biological samples with recovery values in the range of 99.91%-101.91%. (C) 2014 Elsevier B.V. All rights reserved.