文献类型：期刊文献

中文题名：黄芪扶正颗粒治疗心力衰竭BNP疗效观察

英文题名：Treatment of Heart Failure BNP Astragalus Righting Efficacy

作者：蒙占权[1];李应东[1]

第一作者：蒙占权

机构：[1]甘肃中医学院附属医院,甘肃兰州730020

第一机构：甘肃中医药大学第二附属医院

年份：2014

卷号：0

期号：19

起止页码：131

中文期刊名：医学信息（医学与计算机应用）

外文期刊名：Medical Information

语种：中文

中文关键词：慢性心力衰竭;黄芪扶正颗粒;BNP

外文关键词：Chronic heart failure;Astragalus righting particles;BNP

摘要：目的探讨黄芪扶正颗粒治疗心力衰竭的临床疗效。方法收集60例慢性心力衰竭患者临床资料,随机分为两组,各30例。对照组给予抗心衰基础治疗,治疗组加用黄芪扶正颗粒。对比两组患者治疗总有效率、心室功能、BNP水平以及不良反应发生情况。结果治疗组总有效率显著高于对照组(P<0.05);治疗后,治疗组左心室射血分数、心输出量、E/A与治疗前和对照组相比,均有显著性差异(P<0.01,P<0.05);治疗后,两组患者BNP水平均有显著改善,但是治疗组程度较对照组显著(P<0.05)。观察组对美托洛尔、卡托普利的耐受剂量显著高于对照组(P<0.05)。结论黄芪扶正颗粒治疗慢性心力衰竭安全有效,能够改善患者左心室功能,提高机体对美托洛尔、卡托普利的耐受剂量,利于BNP水平恢复。
Objective To investigate the clinical ef icacy of treatment of heart failure Astragalus righting particles.Methods The clinical data of patients with chronic heart failure,60 patients were randomly divided into two groups,each of 30 cases.The control group received basic anti-heart failure treatment,the treatment group Astragalus righting particles.Contrast the treatment of patients with total ef ective rate,ventricular function,BNP levels and adverse events.Results The total ef ective rate was significantly higher(<0.05);After treatment,the treatment group,left ventricular ejection fraction,cardiac output,front E/A treatment compared with the control group,there were significant dif erences(<0.01,<0.05);after treatment,BNP levels were significantly improved in both groups,but the extent of the treatment group compared with the control group was significantly(<0.05).Tolerated dose group for observation metoprolol,captopril significantly higher for the control group(<0.05).Conclusion Astragalus righting particles safe and ef ective treatment of chronic heart failure can improve left ventricular function,improve the body's tolerance dose of metoprolol,captopril,BNP levels conducive to recovery.