文献类型：期刊文献

中文题名：黄芪产品半固体制备工艺优选

英文题名：Optimization of the Semi-solid Preparation Process of Huangqi(Astragali Radix)Based on Box-Behnken Response Surface Methodology

作者：郭清毅[1];李国峰[1,2];李咸慰[1,2];宋沁洁[1,2];张娟娟[1];李东辉[1,2];吴红伟[1,2];李越峰[1,2]

第一作者：郭清毅

机构：[1]甘肃中医药大学,甘肃兰州730000;[2]甘肃省中药制药工艺工程研究中心,甘肃兰州730000

第一机构：甘肃中医药大学

年份：2023

卷号：25

期号：1

起止页码：30

中文期刊名：辽宁中医药大学学报

外文期刊名：Journal of Liaoning University of Traditional Chinese Medicine

收录：CSTPCD

基金：国家自然科学基金项目(81460611,81960713,82160750);中央引导地方科技发展专项资金项目(30440323);国家药品监督管理局中药材及饮片质量控制重点实验室项目(2020GSMPA-KL15);甘肃道地药材产业关键技术及其组方的基础与开发应用研究项目(GSSYLXM-05);甘肃省教育厅产业支撑计划项目(2021CYZC-21);甘肃省中药制药工艺工程研究中心开放课题(ZYGY202003);科技创新服务平台建设项目(18JR2TA017);民生科技专项(科技特派员专题)(20CX9NA070);甘肃省高等学校产业支撑计划项目(2020C-09)。

语种：中文

中文关键词：黄芪;产品半固体;Box-Behnken响应面法;制备工艺

外文关键词：Huangqi(Astragali Radix);semi-solid product;Box-Behnken response surface method;preparation technology

摘要：目的 优选黄芪产品半固体制备工艺。方法 采用单因素试验及正交试验优选黄芪的最佳提取液,以黄芪浓缩液、木糖醇、复配胶及柠檬酸的加入量为考察因素,以产品的感官评分为评价指标,采用Box-Behnken响应面法优化黄芪产品半固体制备工艺。结果 黄芪的最佳提取液工艺为料液比1∶10,提取时间1 h,提取次数3次。黄芪产品半固体最佳制备工艺为黄芪浓缩液加入量11.0%,木糖醇加入量9.0%,复配胶加入量1.0%,柠檬酸加入量0.11%。结论 该研究所制备的产品半固体呈半透明,工艺简便易行,具有一定的开发应用前景。
Objective To optimize the semi-solid preparation process of Huangqi(Astragali Radix)products. Methods Single factor test and orthogonal test were used to select the best extract of Huangqi(Astragali Radix),taking Huangqi(Astragali Radix)concentrate,xylitol,gel and thickening agent and citric acid as the investigating factors,and the sensory score of the product as evaluation The index uses Box-Behnken response surface method to optimize the preparation process of Huangqi(Astragali Radix)semi-solid products. Results The best extraction process of Huangqi(Astragali Radix)was material-liquid ratio(1∶10),extraction time 1 h,and extraction times 3 times. The best preparation process for semi-solid Huangqi(Astragali Radix)products:added amount of Huangqi(Astragali Radix)concentrate at 11.0%,xylitol at 9.0%,gel and thickener ratio at 1.0%,citric acid at 0.11%. Conclusion The semi-solid product prepared in this research is semi-transparent,the process is simple and easy to implement,and has certain development and application prospects.