文献类型：期刊文献

英文题名：Review of Codonopsis Radix biological activities: A plant of traditional Chinese tonic

作者：Shi, Qi[1];Chen, Zhengjun[1];Yang, Jie[2];Liu, Xuxia[1];Su, Yuanjin[1];Wang, Miao[1];Xi, Jiayu[1];Yang, Fude[1];Li, Fang[1]

第一作者：Shi, Qi

通信作者：Yang, FD[1];Li, F[1]

机构：[1]Gansu Univ Chinese Med, Coll Pharm, 35,Dingxi East Rd, Lanzhou 730000, Peoples R China;[2]Beijing Univ Chinese Med, Sch Tradit Chinese Med, Beijing 100029, Peoples R China

第一机构：甘肃中医药大学药学院（西北中藏药协同创新中心办公室）

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Coll Pharm, 35,Dingxi East Rd, Lanzhou 730000, Peoples R China.|[1073501e14fb35863569f]甘肃中医药大学药学院（西北中藏药协同创新中心办公室）;[10735]甘肃中医药大学;

年份：2024

卷号：332

外文期刊名：JOURNAL OF ETHNOPHARMACOLOGY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001249881900001)】；

基金：We are thankful to financial support from the Science and Technology Project of Gansu Province (grant number 21JR1RA271) Ministry of Science and Technology (grant number 2018YFC1706305) , the Industrial Support Program of Colleges and Universities in Gansu Province (grant number 2021CYZC-40) , Gansu Provincial Key R & D Program-Social Development (grant number 23YFFA0069) , Open Project of Gansu Traditional Chinese Medicine Research Center for 2022-2023 (grant number zyzx-2023-10) .

语种：英文

外文关键词：Codonopsis radix; Tonic effects; Medicine-food dual purpose/usage; Potential preventive/health-promoting medi-cine; Suboptimal health status

摘要：Ethnopharmacological relevance: Codonopsis Radix, commonly known as Dangshen in Chinese, is frequently used to treat deficiencies of spleen and lung Qi, gastrointestinal discomfort, fatigue, asthmatic breathing, sallow complexion, lack of strength, shortness of breath, deficiencies of both Qi and blood, as well as impairments to both Qi and body fluids in suboptimal health status. Aim of the review: This review systematically expounds on the modern pharmacological studies related to the use of Codonopsis Radix in invigorating Qi and nourishing the body in recent years. The aim is to provide theoretical research and reference for the in-depth and systematic exploration and development of the applications of Codonopsis Radix in the fields of food and medicine. Materials and methods: This study employs "Codonopsis Radix," "Codonopsis," and "Dangshen" as keywords to gather pertinent information on Codonopsis Radix medicine through electronic searches of classical literature and databases such as PubMed, Elsevier, Google Scholar, Wiley, EMBASE, Cochrane Library, Web of Science, CNKI, Wanfang, VIP, and Baidu Scholar. Results: From previous studies, activities such as immune system modulation, gastrointestinal motility regulation, cardiac function revitalization, lung function improvement, blood circulation enhancement, aging process deceleration, learning and memory augmentation, fatigue resistance enhancement, and liver and kidney damage protection of Codonopsis Radix have been reported. Recognized as an important medicine and food homologous traditional Chinese herbal remedy for supplementing deficiencies, its mode of action is multi-elemental, multisystemic, multi-organ, multi-mechanistic, and multi-targeted. Furthermore, the benefits of its tonic surpass its therapeutic value, establishing it as an extraordinary preventive and therapeutic medicine. Conclusions: With its long history of traditional applications and the revelations of contemporary pharmacological research, Codonopsis Radix exhibits great potential as both a therapeutic agent and a dietary supplement for further research in medicine, nutrition, and healthcare.