文献类型：期刊文献

英文题名：Non-coding RNAs in Regulating Tumor Angiogenesis

作者：Song, Xin[1];Guo, Yanan[2];Song, Peng[3,4];Duan, Dongzhu[5,6];Guo, Wenjing[2]

第一作者：Song, Xin

通信作者：Guo, WJ[1];Song, P[2];Song, P[3];Duan, DZ[4];Duan, DZ[5]

机构：[1]Lanzhou Univ Technol, Sch Life Sci & Engn, Lanzhou, Peoples R China;[2]Gansu Univ Tradit Chinese Med, Sch Tradit Chinese & Western Med, Lanzhou, Peoples R China;[3]Gansu Univ Chinese Med, Affiliated Hosp, Lanzhou, Peoples R China;[4]Key Lab Prevent & Treatment Chron Dis TCM, Lanzhou, Peoples R China;[5]Baoji Univ Arts & Sci, Shaanxi Key Lab Phytochem, Baoji, Peoples R China;[6]Baoji Univ Arts & Sci, Coll Chem & Chem Engn, Baoji, Peoples R China

第一机构：Lanzhou Univ Technol, Sch Life Sci & Engn, Lanzhou, Peoples R China

通信机构：[1]corresponding author), Gansu Univ Tradit Chinese Med, Sch Tradit Chinese & Western Med, Lanzhou, Peoples R China;[2]corresponding author), Gansu Univ Chinese Med, Affiliated Hosp, Lanzhou, Peoples R China;[3]corresponding author), Key Lab Prevent & Treatment Chron Dis TCM, Lanzhou, Peoples R China;[4]corresponding author), Baoji Univ Arts & Sci, Shaanxi Key Lab Phytochem, Baoji, Peoples R China;[5]corresponding author), Baoji Univ Arts & Sci, Coll Chem & Chem Engn, Baoji, Peoples R China.|[10735b845793de6ae2b30]甘肃中医药大学第二附属医院;[10735]甘肃中医药大学;

年份：2021

卷号：9

外文期刊名：FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

收录：;Scopus(收录号：2-s2.0-85116460778);WOS:【SCI-EXPANDED(收录号:WOS:000703769900001)】；

基金：This work was supported by the National Natural Science Foundation of China (81803779); the Gansu Province Science Foundation for Distinguished Young Scholars (20JR10RA348); The National Natural Science Foundation of Shaanxi Province (2018JQ2051); the Gansu Province Science Foundation for B Program (1508RJZA018) from Gansu Provincial Science and Technology Department; the Open Project of Research Center of Traditional Chinese Medicine, Gansu Province (zyzx-2020-zx1); the Open Project of Key Laboratory of Prevention and Treatment for Chronic Diseases by TCM in Gansu Province (GSMBKY2015-01); and the Gansu Province Health Industry Scientific Research Program Management Project (GWGL2014-53).

语种：英文

外文关键词：ncRNA; tumor metabolism; tumor angiogenesis; molecular mechanism; biological function

摘要：Non-coding RNAs (ncRNAs) are RNAs that do not encode proteins, but perform biological functions in various physiological and pathological processes, including cancer formation, inflammation, and neurological diseases. Tumor blood vessels are a key target for cancer management. A number of factors regulate the angiogenesis of malignant tumors. NcRNAs participate in the regulation of tumor angiogenesis. Abnormal expression of ncRNAs act as tumor suppressors or oncogenes to affect the development of tumors. In this review we summarized the biological functions of ncRNAs, and discussed its regulatory mechanisms in tumor angiogenesis. This article will provide new insights for the research of ncRNAs in tumor angiogenesis.