文献类型：期刊文献

中文题名：2014-2019年平凉市手足口病流行病学及病原特征分析

英文题名：Epidemiological and pathogenic characteristics analysis of hand-foot-mouth disease in Pingliang City from 2014 to 2018

作者：孔慧娟[1];王金霞[1];王新华[1];刘新凤[2];任真[1];杨旭[1];王馨[1];宋皎[1];倪文婷[1];梁可可[1];魏兴民[1];蒋小娟[2]

第一作者：孔慧娟

机构：[1]甘肃中医药大学,兰州730000;[2]甘肃省疾病预防控制中心

第一机构：甘肃中医药大学

年份：2021

卷号：37

期号：7

起止页码：635

中文期刊名：医学动物防制

外文期刊名：Journal of Medical Pest Control

收录：CSTPCD

基金：甘肃省高校科研项目(2017A-058);甘肃中医药大学教学改革项目(ZH-201502,PYJH-2016-13)。

语种：中文

中文关键词：手足口病;流行特征;病原体;疫情;分析

外文关键词：Hand-foot-mouth disease;Epidemiological characteristics;Pathogen;Epidemic;Analysis

摘要：目的分析2014-2019年平凉市手足口病流行病学及病原学特征,为该市手足口病的预防控制提供参考依据。方法采用描述性流行病学方法对手足口病三间分布及病原学构成进行统计分析。结果 2014-2019年平凉市手足口病报告病例3 072例,其中重症病例9例,平均年报告发病率为24.28/10万。发病高峰主要集中在5-8月(2 318例,占比83.80%),2014年10-11月出现次高峰,2019年9月出现次小高峰。病例的地区分布中灵台县年均发病率最高,为44.57/10万。人群分布中发病主要为5岁以下儿童(2 733例,占比90.27%),其中1岁组例数最多(1 077例,占比35.06%)。男性发病率高于女性(χ^(2)=134.567,P<0.01),职业分布以散居儿童为主(2 247例,占比73.14%)。不同年份手足口病病原构成比差异有统计学意义(χ^(2)=72.173,P<0.01),2014年的优势毒株为EV 71型,2015-2018年的优势毒株为其他肠道病毒,2019年优势毒株为Cox A16型。结论平凉市手足口病的发病人群以5岁以下幼儿为主,具有明显的时间聚集性特征。应在每年手足口病高发时段前期加强对重点人群和重点地区的宣传教育,做好综合防控工作。
Objective To analyze the epidemiological and pathogenic characteristics of hand-foot-mouth disease(HFMD)in Pingliang City from 2014 to 2019,and to provide a reference basis for the prevention and control of HFMD.Methods Statistical analysis of the distribution and etiological composition of the three intervals of HFMD using descriptive epidemiological methods.Results From 2014 to 2019,there were 3072 cases of HFMD were reported in Pingliang City,including 9 severe cases,with an average annual reported incidence of 24.28/100000.The peak incidence was concentrated in May-August(2318 cases,83.80%),with a secondary peak in October-November 2014 and a minor peak in September 2019.The regional distribution of cases was the highest in Lingtai County with an average annual incidence of 44.57/100000.The population distribution was dominated by children under 5 years old(2733 cases,90.27%),with the highest number of cases in the 1-year-old group(1077 cases,35.06%).The incidence rate of male was higher than that of female(χ^(2)=134.567,P<0.01),and the occupational distribution was dominated by scattered children(2247 cases,73.14%).The difference of pathogen composition ratio of HFMD in different years was statistically significant(χ^(2)=72.173,P<0.01).The dominant strain in 2014 was EV 71,and the dominant strain from 2015 to 2018 was other enterovirus.The predominant strain in 2019 was Cox A16.Conclusion The incidence of HFMD in Pingliang is mainly among children under 5 years of age,and has obvious characteristics of temporal aggregation.Publicity and education for key populations and areas should be strengthened in the early part of the high incidence of HFMD each year,comprehensive prewention and control work should be done.