文献类型：期刊文献

中文题名：基于中医传承辅助系统分析小儿外感发热的用药规律研究

英文题名：Researches on medication rules in treating infantile exogenous fever by TCM inheritance support system

作者：李洪海[1];韩琦[1];李萍[1];梁永林[1]

第一作者：李洪海

机构：[1]甘肃中医药大学基础医学院,甘肃兰州730000

第一机构：甘肃中医药大学基础医学院（敦煌医学研究所）

年份：2017

卷号：13

期号：3

起止页码：87

中文期刊名：中医儿科杂志

外文期刊名：Journal of Pediatrics of Traditional Chinese Medicine

语种：中文

中文关键词：小儿外感发热;中医传承辅助系统;基本病机;用药规律

外文关键词：infantile exogenous fever; TCM inheritance support system ; basic pathogenesis ; medication rules

摘要：目的基于中医传承辅助系统2.5软件,分析和总结历代中医治疗小儿外感发热的方剂,以方测证,探寻小儿外感发热的用药规律。方法筛选《中医方剂大辞典》中与治疗小儿外感发热有关的处方,运用中医传承辅助系统的数据挖掘方法频次分析、组方规律分析、熵层次聚类分析,统计数据并分析其结果,探究小儿外感发热的用药规律。结果通过对《中医方剂大辞典》中收录的122个用于治疗小儿外感发热的方剂分析,共使用药物170味,最常用的药物分别为甘草、黄芩、大黄、人参、茯苓。再通过软件进一步分析,得到常用药物的组合有31个,3味药的核心组合共32个,新方的核心药物组合18个,新方9个。结论小儿外感发热的基本病机为外感邪气,脾胃虚弱,心气不降。治疗小儿外感发热之时应当解表清热泻火以祛邪,宁心益气健脾以扶正,同时,针对小儿特殊体质易出现的神昏、惊厥等症状,施以宁心息风、开窍醒神等药物。
Objective Analyzing and summarizing the ancient prescriptions in TCM to explore medication rules in treating infantile exogenous fever by TCM inheritance support system. Methods After selected TCM prescriptions of treating infantile exogenous fever from TCM Prescriptions Dictionary, statistical data was analyzed to explore medication rules in treating infantile exogenous fever by data mining and medication rules analysis in the software. Results After analyzed of 122 prescriptions of treating infantile exogenous fever in TCM Prescriptions Dictionary, 170 kinds of herbal medicine were applied totally, the most common drugs were Gancao（Glycyrrhizae） ,Huangqin（ Scutellariae Baicalensis）, Dahuang （ Rheum Officinale ）, Renshen （ Ginseng）, Fuling （ Poria Cocos）. Making a further analysis in software, there was 31 common herbal combinations, 32 core combinations from 3 kinds of herbal medicine, 18 core combinations of mew medicine, 9 new prescriptions. Conclusion Since deficiency of spleen-stomach and insufficiency of heart qi were basic pathogenesis of infantile exogenous fever, its treatment should focus on clearing heat and fire to eliminate pathogens, tonifying qi and calming heart to strengthen body resistance. At the same time, some medicine worked on calming endogenous wind and inducing resuscitation should be applied to treat some syndromes of infantile special constitution, like coma, convulsions and so on.