文献类型：期刊文献

英文题名：Mediterranean diet related to 3-year incidence of cognitive decline: results from a cohort study in Chinese rural elders

作者：Feng, Yuping[1];Wang, Jiancheng[2];Zhang, Rong[1];Wang, Yunhua[3];Wang, Jing[1];Meng, Hongyan[1];Cheng, Hu[3];Zhang, Juxia[4]

第一作者：Feng, Yuping

通信作者：Zhang, JX[1]

机构：[1]Gansu Univ Chinese Med, Sch Nursing, Lanzhou, Peoples R China;[2]Hosp Gansu Hlth Vocat Coll, Dept Gen Practice Med, Lanzhou, Peoples R China;[3]Lanzhou Univ, Sch Publ Hlth, Lanzhou, Peoples R China;[4]Gansu Prov Hosp, Clin Educ Dept, Lanzhou 730000, Gansu, Peoples R China

第一机构：甘肃中医药大学护理学院

通信机构：[1]corresponding author), Gansu Prov Hosp, Clin Educ Dept, Lanzhou 730000, Gansu, Peoples R China.

年份：2024

外文期刊名：NUTRITIONAL NEUROSCIENCE

收录：;Scopus(收录号：2-s2.0-85190445109);WOS:【SCI-EXPANDED(收录号:WOS:001200476900001)】；

基金：This work was supported by the National Natural Science Foundation of China under Grant [number: 72264002], the China Medical Education Association Project under Grant [number: 2022KTZ010], and the research Fund project of Gansu Provincial Hospital under Grant [numbers: 22GSSYYD-70].

语种：英文

外文关键词：Cognitive decline; MMSE ?; Mediterranean diet; MEDAS ?; risk factor; follow-up; rural elders; diet

摘要：Objective: This study aims to examine the effect of the Mediterranean diet (MeDi) on cognitive decline among the Chinese elderly with a 3-year follow-up. Methods: This study is divided into two waves: wave-1 January 2019 to June 2019 (n = 2313); wave-2 January 2022 to March 2022 (n = 1648). MeDi scores were calculated from the Mediterranean Diet Adherence Screener (MEDAS), with the scoring of low compliance (0-6 points) and high compliance (7-14 points). The Mini-Mental State Examination (MMSE) was used to assess cognitive function. An MMSE score dropping >= 2 points from baseline was defined as cognitive decline. The relationships between MeDi score and cognitive decline were analyzed by linear regression models or Binary logistic regression. Results: During the 3-year follow-up, 23.8% of patients exhibited cognitive decline. The study revealed a significant difference in MMSE score changes between low and high MeDi adherence groups (p < 0.001). MeDi score was negatively correlated with cognitive deterioration (beta = -0.020, p = 0.026). MeDi score was only negatively associated with cognitive decline in the female subgroup aged >= 65 years (beta = -0.034, p = 0.033). The food beans (OR = 0.65, 95%CI:0.51, 0.84), fish (OR = 0.72, 95%CI:0.54, 0.97), and cooked vegetables (OR = 0.68, 95%CI:0.53, 0.84) were protective factors for cognitive decline. Conclusions: This study suggests that greater adherence to the MeDi is linked to a reduced risk of cognitive decline in elderly people. However, this is found only in women who are 65 years old or older. It also found long-term adherence to beans, fish, and vegetables are more effective in improving cognitive function.