文献类型：期刊文献

英文题名：Analysis of current status and risk factors of catheter infection in hemodialysis patients in Gansu Province, China

作者：Sun, Yi[1];Feng, Yujuan[2];Zhang, Xiaoliang[2];Yao, Ziyan[1];Zhang, Linna[1];Li, Xiarong[3];Zhu, Zeshan[4];Cai, Ling[5];Zhang, Yinghua[5];Zhang, Haojun[6]

第一作者：孙勇;孙尧

通信作者：Zhang, HJ[1]

机构：[1]Gansu Univ Tradit Chinese Med, Sch Publ Hlth, Lanzhou 730000, Peoples R China;[2]Second Peoples Hosp Gansu Prov, Dept Hosp Infect Management & Publ Hlth, Lanzhou 730000, Peoples R China;[3]Lanzhou Univ, Sch Publ Hlth, Lanzhou 730000, Peoples R China;[4]Gansu Prov Hlth Commiss, Hosp Management Ctr, Lanzhou 730010, Peoples R China;[5]Gansu Prov Peoples Hosp, Hosp Infect Management Sect, Lanzho 730000, Peoples R China;[6]Second Peoples Hosp Gansu Prov, Off President, Lanzhou 730000, Peoples R China

第一机构：甘肃中医药大学公共卫生学院

通信机构：[1]corresponding author), Second Peoples Hosp Gansu Prov, Off President, Lanzhou 730000, Peoples R China.

年份：2026

卷号：16

期号：1

外文期刊名：SCIENTIFIC REPORTS

收录：;Scopus(收录号：2-s2.0-105039631481);WOS:【SCI-EXPANDED(收录号:WOS:001769779600007)】；

基金：China National Natural Science Foundation, 72064002. Gansu Province Health Sector Project, GSWSKY-2019-10. Northwest University for Nationalities Central University Fund Project, 31920240079.

语种：英文

外文关键词：Hemodialysis; Central venous catheter; Bloodstream infection; Pathogenic bacteria; Risk factors

摘要：Catheter-related bloodstream infection (CRBSI) significantly increases the mortality rate among hemodialysis patients. This study aims to analyze the prevalence of CRBSI and its risk factors in hemodialysis patients, providing actionable recommendations using Gansu Province as a case study. A cross-sectional study was conducted involving 540 hemodialysis patients with central venous catheters, selected from 28 hospitals across seven cities in Gansu Province. Patients were divided into an infected group (90 cases) and a non-infected group (450 cases). Data collected included clinical characteristics, infection rates, pathogens, and their antibiotic sensitivity. Logistic regression analysis was performed to identify risk factors for CRBSI. The CRBSI incidence rate was 16.67%. Gram-positive bacteria predominated among isolated pathogens (59.02%), with Staphylococcus aureus (31.15%) being the most common. Logistic regression identified hospital level, diabetic nephropathy as the primary disease, anemia, hypoproteinemia, and elevated serum ferritin as significant risk factors. CRBSI incidence in Gansu's hemodialysis patients is high, with Gram-positive bacteria as the dominant pathogens. Key risk factors include hospital level, diabetic nephropathy, anemia, hypoproteinemia, and elevated serum ferritin. Targeted interventions are necessary to reduce CRBSI occurrence.